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Titolo:
PROLONGATION OF THE QT-INTERVAL DURING INDUCTION OF ANESTHESIA IN PATIENTS WITH CORONARY-ARTERY DISEASE
Autore:
LISCHKE V; WILKE HJ; PROBST S; BEHNE M; KESSLER P;
Indirizzi:
JW GOETHE UNIV HOSP,DEPT ANESTHESIOL & RESUSCITAT,THEODOR STERN KAI 7D-60590 FRANKFURT GERMANY
Titolo Testata:
Acta anaesthesiologica Scandinavica
fascicolo: 2, volume: 38, anno: 1994,
pagine: 144 - 148
SICI:
0001-5172(1994)38:2<144:POTQDI>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEART-RATE; VENTRICULAR ARRHYTHMIAS; MYOCARDIAL-INFARCTION; SUDDEN-DEATH; PRESSURE; ECG;
Keywords:
ANESTHESIA; CORONARY HEART DISEASE; ELECTROCARDIOGRAM; QT INTERVAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
V. Lischke et al., "PROLONGATION OF THE QT-INTERVAL DURING INDUCTION OF ANESTHESIA IN PATIENTS WITH CORONARY-ARTERY DISEASE", Acta anaesthesiologica Scandinavica, 38(2), 1994, pp. 144-148

Abstract

During induction of anesthesia in 60 patients undergoing coronary artery bypass grafting (CABG), we measured the QT-interval (QTI) in the ECG, heart rate (HR) and mean arterial pressure (MAP). Based on the HR,we corrected the QT-interval (QTcI). Prior to induction, six patients(10%) already had abnormal prolongation of QTcI (greater than or equalto 440 ms). After injection of fentanyl and vecuronium, the QTcI increased significantly (P < 0.01); to a far lesser extent after injectionof hypnotics (i.e. etomidate, midazolam or propofol). Orotracheal intubation caused significant shortening of QTcI (P < 0.01). HR decreasedmarkedly after injection of fentanyl. MAP decreased, however, only after injection of hypnotics. In the immediate post intubation period, HR and MAP increased significantly. The various hypnotics produced no significant difference in HR and QTcI at any measurement point. MAP changed only after injection of hypnotics. The decrease of HR and MAP during induction of anesthesia is thought to result from a corresponding reduction of adrenosympathetic stimulation. We believe that QTcI is similarly influenced.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/10/20 alle ore 05:56:53