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Titolo:
A CLINICAL AND NEUROPATHOLOGIC STUDY OF SILK SUTURE AS AN EMBOLIC AGENT FOR BRAIN ARTERIOVENOUS-MALFORMATIONS
Autore:
DEVEIKIS JP; MANZ HJ; LUESSENHOP AJ; CAPUTY AJ; KOBRINE AI; SCHELLINGER D; PATRONAS N;
Indirizzi:
UNIV MICHIGAN HOSP,DEPT RADIOL B1D530,1500 E MED CTR DR ANN ARBOR MI 48109 GEORGETOWN UNIV HOSP,DEPT RADIOL NEURORADIOL WASHINGTON DC 20007 GEORGETOWN UNIV HOSP,DEPT PATHOL NEUROPATHOL WASHINGTON DC 20007 GEORGETOWN UNIV HOSP,DEPT SURG NEUROSURG WASHINGTON DC 00000
Titolo Testata:
American journal of neuroradiology
fascicolo: 2, volume: 15, anno: 1994,
pagine: 263 - 271
SICI:
0195-6108(1994)15:2<263:ACANSO>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
PREOPERATIVE EMBOLIZATION; POLYVINYL-ALCOHOL; THERAPEUTIC EMBOLIZATION; FOLLOW-UP; EXPERIENCE; AVMS; MANAGEMENT; OCCLUSION; BUCRYLATE; SURGERY;
Keywords:
ARTERIOVENOUS MALFORMATIONS, CEREBRAL; ARTERIOVENOUS MALFORMATIONS, EMBOLIZATION; INTERVENTIONAL MATERIALS, EMBOLIC AGENTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
J.P. Deveikis et al., "A CLINICAL AND NEUROPATHOLOGIC STUDY OF SILK SUTURE AS AN EMBOLIC AGENT FOR BRAIN ARTERIOVENOUS-MALFORMATIONS", American journal of neuroradiology, 15(2), 1994, pp. 263-271

Abstract

PURPOSE: To evaluate the safety and efficacy of silk suture as an agent for preoperative embolization of cerebral arteriovenous malformations. METHODS: Clinical and histopathologic results were analyzed in sixpatients who underwent embolization of cerebral arteriovenous malformations using silk suture in combination with other agents. RESULTS: Three of the patients treated with silk hemorrhaged after embolization, and two of these patients died. Neuropathologic analysis of four patients showed acute perivascular inflammation, sometimes quite severe. CONCLUSIONS: The inflammatory response to silk may explain its effectiveness in producing vascular occlusion. However, a fulminate vasculitis theoretically can predispose to delayed hemorrhage. Other problems with silk include the pressure required to inject the agent and the inability to determine the final site of deposition of the silk. Although other embolic agents may share some of these potential difficulties, wefeel that the disadvantages outweigh the advantages of silk as an embolic agent.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 20:19:04