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Titolo:
COMPARISON OF COVERED VERSUS UNCOVERED WIRE MESH STENTS IN THE CANINEBILIARY-TRACT
Autore:
SILVIS SE; SIEVERT CE; VENNES JA; ABEYTA BK; BRENNECKE LH;
Indirizzi:
VET AFFAIRS MED CTR,DEPT MED,GASTROENTEROL SECT 111D,1 VET DR MINNEAPOLIS MN 55417 UNIV MINNESOTA,DEPT MED MINNEAPOLIS MN 55455 PATHOL ASSOCIATES INC,DEPT MED FREDERICK MD 00000
Titolo Testata:
Gastrointestinal endoscopy
fascicolo: 1, volume: 40, anno: 1994,
pagine: 17 - 21
SICI:
0016-5107(1994)40:1<17:COCVUW>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
SELF-EXPANDABLE STENTS; METAL STENTS; OBSTRUCTIVE-JAUNDICE; RANDOMIZED TRIAL; ENDOPROSTHESIS; EXPERIENCE; INSERTION; STRICTURES; DRAINAGE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
S.E. Silvis et al., "COMPARISON OF COVERED VERSUS UNCOVERED WIRE MESH STENTS IN THE CANINEBILIARY-TRACT", Gastrointestinal endoscopy, 40(1), 1994, pp. 17-21

Abstract

Self-expanding wire mesh stents have been developed for endoscopic placement across malignant biliary strictures, but tumor ingrowth may limit the usefulness of open mesh stents. We reasoned that coating the wire mesh might prevent tumor ingrowth. Tissue response to covered and uncovered stents was compared in dogs. Stents were surgically placed in the bile ducts of 22 mongrel dogs through the sphincter of Oddi. Either a silicone-covered stent or an uncovered stent was inserted. Liverfunction test values remained normal throughout a 1- or 3-month study. Necropsy revealed that all ducts were unobstructed. Bile duct histologic examination revealed mild-to-moderate cellular infiltration in all animals. Mucosal hyperplasia was more marked in the animals with uncovered stents and the bare wires became deeply embedded in bile duct epithelium, whereas the wires of covered stents did not. We conclude that covered stents are well tolerated by the canine bile duct. These results suggest that such stents may be removable, making self-expandingmetal stents an appropriate treatment for both benign and malignant biliary strictures.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 16:13:29