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Titolo:
FLUMAZENIL HAS AN ANXIOLYTIC EFFECT IN SIMULATED STRESS
Autore:
KAPCZINSKI F; CURRAN HV; GRAY J; LADER M;
Indirizzi:
INST PSYCHIAT,MRC,CLIN PSYCHOPHARMACOL SECT,DE CRESPIGNY PK,DENMARK HILL LONDON SE5 8AF ENGLAND INST PSYCHIAT,MRC,CLIN PSYCHOPHARMACOL SECT LONDON SE5 8AF ENGLAND
Titolo Testata:
Psychopharmacology
fascicolo: 1, volume: 114, anno: 1994,
pagine: 187 - 189
Fonte:
ISI
Lingua:
ENG
Soggetto:
BENZODIAZEPINE ANTAGONIST;
Keywords:
FLUMAZENIL; ANXIETY; ENDOGENOUS BENZODIAZEPINES; PUBLIC SPEAKING;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
F. Kapczinski et al., "FLUMAZENIL HAS AN ANXIOLYTIC EFFECT IN SIMULATED STRESS", Psychopharmacology, 114(1), 1994, pp. 187-189

Abstract

This study was designed to test whether or not flumazenil (1 mg IV) would change levels of anxiety induced by simulation of public speaking(PSS). Forty normal volunteers were randomly allocated in a parallel groups design to treatment with flumazenil or placebo (double-blind) and one of two stress conditions (PSS/control task). PSS increased anxiety and flumazenil antagonized this effect. The anxiolytic activity offlumazenil was particularly strong on anticipatory anxiety measures. The results were discussed in terms of the involvement of endogenous benzodiazepine-type ligands in the regulation of the human response to stress.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 04:23:04