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Titolo:
ONTOGENY OF NEUROPEPTIDES IN THE RAT URINARY-BLADDER
Autore:
EKSTROM J; EKMAN R; HAKANSON R;
Indirizzi:
UNIV GOTEBORG,DEPT PHARMACOL,MEDICINAREGATAN 7 S-41390 GOTHENBURG SWEDEN UNIV GOTEBORG,DEPT NEUROCHEM & PSYCHIAT GOTHENBURG SWEDEN LUND UNIV,DEPT PHARMACOL LUND SWEDEN
Titolo Testata:
Regulatory peptides
fascicolo: 1, volume: 50, anno: 1994,
pagine: 23 - 28
SICI:
0167-0115(1994)50:1<23:OONITR>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
CAPSAICIN-SENSITIVE INNERVATION; GENE-RELATED PEPTIDE; SUBSTANCE-P; POSTNATAL-DEVELOPMENT; MICTURITION REFLEX; NERVE-FIBERS; ORIGIN;
Keywords:
CGRP; NPY; SP; VIP; URINARY BLADDER; ONTOGENY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
J. Ekstrom et al., "ONTOGENY OF NEUROPEPTIDES IN THE RAT URINARY-BLADDER", Regulatory peptides, 50(1), 1994, pp. 23-28

Abstract

Urinary bladders of male rats at ages ranging from I day to 18 monthswere analysed for their neuropeptide content. NPY was detected at birth, VIP and CGRP at 1 week, and SP at 2 weeks. There was then a sharp increase in both the total amounts and concentrations of VIP, CGRP andSP until the rats had reached the age of 3-4 weeks. The total amount of NPY increased in two surges, between 2-3 weeks and between 4-5 weeks. The concentration of NPY showed a biphasic course, a decrease during the first two weeks and then an increase. In adults the total amounts of substance P and CGRP were higher than in younger animals, whereasthat of VIP was lower. Following peaks at 3-8 weeks, the concentrations of VIP and substance P decreased with age, whereas that of CGRP remained unchanged. NPY was not followed beyond 8 weeks. The present findings offer a framework for future studies aimed at elucidating the functional role of neuropeptides in the regulation of micturition.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 11:01:34