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Titolo:
DEVELOPMENT, STRUCTURE AND FUNCTION OF THE CRANIAL SUSPENSORY LIGAMENTS OF THE MAMMALIAN GONADS IN A CROSS-SPECIES PERSPECTIVE - THEIR POSSIBLE ROLE IN EFFECTING DISTURBED TESTICULAR DESCENT
Autore:
VANDERSCHOOT P; EMMEN JMA;
Indirizzi:
ERASMUS UNIV ROTTERDAM,FAC MED & HLTH SCI,DEPT ENDOCRINOL & REPROD,POB 1738 NL-3000 DR ROTTERDAM NETHERLANDS
Titolo Testata:
Human reproduction update
fascicolo: 5, volume: 2, anno: 1996,
pagine: 399 - 418
SICI:
1355-4786(1996)2:5<399:DSAFOT>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
COSTO-UTERINE MUSCLE; SYMPATHETIC DENERVATION; SEXUAL-DIFFERENTIATION; INDUCED CRYPTORCHIDISM; RAT OVARY; FLUTAMIDE; ANDROGEN; TESTIS; FEMINIZATION; GUBERNACULUM;
Keywords:
CRANIAL SUSPENSORY APPARATUS; CRYPTORCHIDISM; GENITAL DEVELOPMENT; TESTICULAR DESCENT;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
82
Recensione:
Indirizzi per estratti:
Citazione:
P. Vanderschoot e J.M.A. Emmen, "DEVELOPMENT, STRUCTURE AND FUNCTION OF THE CRANIAL SUSPENSORY LIGAMENTS OF THE MAMMALIAN GONADS IN A CROSS-SPECIES PERSPECTIVE - THEIR POSSIBLE ROLE IN EFFECTING DISTURBED TESTICULAR DESCENT", Human reproduction update, 2(5), 1996, pp. 399-418

Abstract

The present review aims to present a perspective on a relatively unknown part of the mammalian internal genitalia: their cranial suspensoryapparatus. This apparatus shows wide divergence of development when examined during the fetal period or during adulthood, in males or females, or in individuals across a variety of species, In rats and other mammalian species the apparatus undergoes a distinct pattern of sexually dimorphic development and fetal testicular androgens are proposed toplay a key role in this process, Extensive development of this suspensory apparatus in females is argued to be a part of the anatomical adaptations of the genital apparatus to support the internal genitalia throughout pregnancy, including the relatively enormous growth towards the time of parturition, Minor development of this apparatus in males is judged to be a part of the anatomical requirements allowing developing testes to become displaced from the dorsal abdominal wall during the first stage of testicular descent, Extensive development of this suspensory apparatus in males generally seems to hinder testicular descent, Accordingly, the apparatus is well developed in so-called testicondspecies which do not show testis descent as a part of their normal male genital development, Furthermore, arguments are adduced that inappropriate and extensive development in species with testis descent may be a key aetiological factor in the disturbance of this process, Diagnosis and treatment of human cryptorchidism might profit from including an analysis of the development and function of (remnants of) the cranial testicular and epididymal suspensory apparatus.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 15:45:50