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Titolo:
SALT, WATER AND SURVIVAL - ACID TESTS AND BASIC ADVANCES IN FLUID THERAPY
Autore:
MICHELL AR;
Indirizzi:
UNIV LONDON,ROYAL VET COLL,DEPT LARGE ANIM MED & SURG,HAWKSHEAD LANE HATFIELD AL9 7TA HERTS ENGLAND
Titolo Testata:
Irish veterinary journal
fascicolo: 1, volume: 47, anno: 1994,
pagine: 3 - 8
SICI:
0368-0762(1994)47:1<3:SWAS-A>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ORAL REHYDRATION SOLUTION; INTESTINAL ELECTROLYTE TRANSPORT; DIARRHEAL DISEASE; CALF DIARRHEA; GLYCINE; EFFICACY; DISTURBANCES; ABSORPTION; BALANCE; GLUCOSE;
Keywords:
DIARRHEA; FLUID THERAPY; ORAL REHYDRATION; ACIDOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
A.R. Michell, "SALT, WATER AND SURVIVAL - ACID TESTS AND BASIC ADVANCES IN FLUID THERAPY", Irish veterinary journal, 47(1), 1994, pp. 3-8

Abstract

Diarrhoea does not just cause fluid and electrolyte disturbances; fundamentally it is a failure of net enteric uptake of sodium and water. The most lethal effects are dehydration, particularly loss of extracellular (ECF) volume, also acidosis and hyperkalaemia. The importance ofsodium in repairing ECF volume, and as the key constituent (alongsideglucose) of oral rehydration solutions (ORS) was emphasised. Misconceptions about the causes of hyponatraemia and hypernatraemia were clarified. The importance of bicarbonate precursors was reaffirmed and arguments surrounding glycine were discussed. Glucose acts through cotransport with sodium, not as an energy source and the problem of energy deficit with conventional ORS was examined. Aspects of the composition of parenteral fluids were also discussed, notably sodium, potassium andbicarbonate precursors as well as the use of ORS in conjunction with parenteral therapy. The opportunity to tailor therapy according to measured changes in plasma composition, especially acidosis, was identified as a major area of clinical progress. Impediments to progress include licensing constraints designed for receptor-active drugs and the tendency for funding bodies to favour blue-sky research rather than genuine improvements in deliverable health care.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 09:25:52