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Titolo:
ECAT ART - A CONTINUOUSLY ROTATING PET CAMERA - PERFORMANCE-CHARACTERISTICS, INITIAL CLINICAL-STUDIES, AND INSTALLATION CONSIDERATIONS IN ANUCLEAR-MEDICINE DEPARTMENT
Autore:
BAILEY DL; YOUNG H; BLOOMFIELD PM; MEIKLE SR; GLASS D; MYERS MJ; SPINKS TJ; WATSON CC; LUK P; PETERS AM; JONES T;
Indirizzi:
HAMMERSMITH HOSP,MRC,CYCLOTRON UNIT,DU CANE RD LONDON W12 0HS ENGLAND HAMMERSMITH HOSP,DEPT NUCL MED LONDON ENGLAND CTI PET SYST KNOXVILLE TN 00000
Titolo Testata:
European journal of nuclear medicine
fascicolo: 1, volume: 24, anno: 1997,
pagine: 6 - 15
SICI:
0340-6997(1997)24:1<6:EA-ACR>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; RETRACTABLE SEPTA; IMAGE-RECONSTRUCTION; SCANNER; SENSITIVITY; DESIGN; BRAIN;
Keywords:
3-DIMENSIONAL IMAGE RECONSTRUCTION; PARTIAL-RING SCANNER; POSITION EMISSION TOMOGRAPHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
D.L. Bailey et al., "ECAT ART - A CONTINUOUSLY ROTATING PET CAMERA - PERFORMANCE-CHARACTERISTICS, INITIAL CLINICAL-STUDIES, AND INSTALLATION CONSIDERATIONS IN ANUCLEAR-MEDICINE DEPARTMENT", European journal of nuclear medicine, 24(1), 1997, pp. 6-15

Abstract

Advances in fully three-dimensional (3D) image reconstruction techniques have permitted the development of a commercial, rotating, partial ring, fully 3D positron emission tomographic (PET) scanner, the ECAT ART. The system has less than one-half the number of bismuth germanate detectors compared with a full ring scanner with the equivalent field of view, resulting in reduced capital cost. The performance characteristics, implications for installation in a nuclear medicine department,and clinical utility of the scanner are presented in this report. Thesensitivity (20 cm diameterx20 cm long cylindrical phantom, no scatter correction) is 11400 cps . kBq(-1). ml(-1). This compares with 5800 and 40500 cps . kBq(-1). ml(-1) in 2D and 3D respectively for the equivalent full ring scanner (ECAT EXACT). With an energy window of 350-650 keV the maximum noise equivalent count (NEC) rate was 27 kcps at a radioactivity concentration of similar to 15 kBq . ml(-1) in the cylinder. Spatial resolution is similar to 6 mm full width at half maximum on axis degrading to just under 8 mm at a distance of 20 cm off axis. Installation and use within the nuclear medicine department does not appreciably increase background levels of radiation on gamma cameras in adjacent rooms and the dose rate to an operator in the same room is 2 mu Sv . h(-1) for a typical fluorine-18 fluorodeoxyglucose (F-18-FDG) study with an initial injected activity of 370 MBq. The scanner has been used for clinical imaging with F-18-FDG for neurological and oncological applications. Its novel use for imaging iron-52 transferrin for localising erythropoietic activity demonstrates its sensitivity and resolution advantages over a conventional dual-headed gamma camera. The ECAT ART provides a viable alternative to conventional full ring PET scanners without compromising the performance required for clinical PETimaging.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 15:42:28