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Titolo:
ROLE OF ADRENERGIC PATHWAYS OF THE MEDIAL PREOPTIC AREA IN ANGII-INDUCED WATER-INTAKE AND RENAL EXCRETION IN RATS
Autore:
BASTOS R; SAAD WA; MENANI JV; RENZI A; SILVEIRA JEN; CAMARGO LAD;
Indirizzi:
PAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL,POB 331,1680 HUMAITA ST BR-14801903 ARARAQUARA SP BRAZIL PAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL BR-14801903 ARARAQUARA SP BRAZIL
Titolo Testata:
Brain research
fascicolo: 1, volume: 636, anno: 1994,
pagine: 81 - 86
SICI:
0006-8993(1994)636:1<81:ROAPOT>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPERIMENTALLY-INDUCED DRINKING; VENTRAL LAMINA TERMINALIS; ANGIOTENSIN-II; PRESSOR-RESPONSES; BLOOD-PRESSURE; INJECTIONS; LESIONS; 6-HYDROXYDOPAMINE; DEPLETION; DEFICITS;
Keywords:
WATER INTAKE; FLUID BALANCE; ELECTROLYTE BALANCE; AV3V REGION; ADRENERGIC RECEPTOR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
R. Bastos et al., "ROLE OF ADRENERGIC PATHWAYS OF THE MEDIAL PREOPTIC AREA IN ANGII-INDUCED WATER-INTAKE AND RENAL EXCRETION IN RATS", Brain research, 636(1), 1994, pp. 81-86

Abstract

In this study, we investigated the participation of adrenergic neurotransmission in angiotensin II- (ANGII)-induced water intake and urinary electrolyte excretion by means of injection of the alpha(1)-, alpha(2)-, and beta-adrenoceptor antagonists and ANGII into the medial preoptic area (MPOA) in rats. Prazosin (an alpha(1)-adrenergic antagonist) antagonized the water ingestion, Na+, K+ and urine excretion induced by ANGII, whereas yohimbine (an alpha(2)-adrenergic antagonist) enhanced the Na+, K+ and urine excretion induced by ANGII. Propranolol (a nonselective beta-adrenoceptor blocker) antagonized the water ingestion and enhanced the Na+ and urine excretion induced by ANGII. Previous treatment with prazosin reduced the presser responses to ANGII, whereas yohimbine had opposite effects. Previous injection of propranolol produced no effects in the presser responses to ANGII. These results suggest that the adrenergic neurotransmission in the MPOA may actively participate in ANGII-induced dipsogenesis, natriuresis, kaliuresis and diuresis in a process that involves alpha(1)-, alpha(2)-, and beta-adrenoceptors.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:55:21