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Titolo:
AGE AND CLINICAL IMMUNITY TO INFECTIONS WITH CHLAMYDIA-TRACHOMATIS
Autore:
ARNO JN; KATZ BP; MCBRIDE R; CARTY GA; BATTEIGER BE; CAINE VA; JONES RB;
Indirizzi:
INDIANA UNIV,SCH MED,DEPT MED,545 BARNHILL DR EM 435 INDIANAPOLIS IN 46202 INDIANA UNIV,SCH MED,DEPT MICROBIOL & IMMUNOL INDIANAPOLIS IN 46202 INDIANAPOLIS PUBL SCH INDIANAPOLIS IN 00000 MARION CTY HLTH DEPT INDIANAPOLIS IN 00000 RICHARD L ROUDEBUSH VET ADM MED CTR INDIANAPOLIS IN 00000
Titolo Testata:
Sexually transmitted diseases
fascicolo: 1, volume: 21, anno: 1994,
pagine: 47 - 52
SICI:
0148-5717(1994)21:1<47:AACITI>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
OUTER-MEMBRANE PROTEIN; SEXUALLY-TRANSMITTED DISEASE; GENITAL-TRACT; WOMEN; CELLS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
J.N. Arno et al., "AGE AND CLINICAL IMMUNITY TO INFECTIONS WITH CHLAMYDIA-TRACHOMATIS", Sexually transmitted diseases, 21(1), 1994, pp. 47-52

Abstract

Background and Objectives: The prevalence of chlamydial infection decreases with age possibly in part because of increasing immunity. Goal of this Study: To determine whether increased age is an independent predictor of decreased chlamydial infection and whether chlamydia-specific antibody titer and blastogenesis increase with age. Study Design: Data from all patients cultured for Chlamydia trachomatis between January 1984 and August 1989 were examined and multiple logistic regressionmodels were used to identify the independent predictors of culture positivity. Antichlamydial antibody titer and chlamydia-specific blastogenesis were examined for a subset of patients for correlation with age. Results: Young age was found to be predictive of chlamydial infection independent of all factors examined in men and women, Antibody titers had no relation to age (n = 245) whereas the level of blastogenesis correlated only weakly with age (n = 155). Conclusions: Assays of systemic immunity do not reflect the protection from chlamydial infection associated with age.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 20:07:35