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Titolo: EXPERIMENTAL-STUDY OF CRYOPRESERVED ALLOGENEIC TRANSFER OF VESSEL - PRELIMINARY-REPORT
Autore: TAKEISHI M; HIRASE Y; KOJIMA T;
- Indirizzi:
- JIKEI UNIV,SCH MED,DEPT PLAST & RECONSTRUCT SURG,MINATO KU,3-25-8 NISHISHIMBASHI TOKYO 105 JAPAN
- Titolo Testata:
- Microsurgery
fascicolo: 1,
volume: 15,
anno: 1994,
pagine: 55 - 62
- SICI:
- 0738-1085(1994)15:1<55:EOCATO>2.0.ZU;2-0
- Fonte:
- ISI
- Lingua:
- ENG
- Tipo documento:
- Note
- Natura:
- Periodico
- Settore Disciplinare:
- Science Citation Index Expanded
- Citazioni:
- NO
- Recensione:
- Indirizzi per estratti:
-
-
-
- Citazione:
- M. Takeishi et al., "EXPERIMENTAL-STUDY OF CRYOPRESERVED ALLOGENEIC TRANSFER OF VESSEL - PRELIMINARY-REPORT", Microsurgery, 15(1), 1994, pp. 55-62
Abstract
It has long been known that the antigenicity of tissues is depressed when they are kept at a very low temperature. In this study, Lewis rats and Brown Norway (B.N.) rats were used because these species are significantly dissimilar at the major histocompatibility complex (MHC) Femoral arteries were harvested from Lewis rats, frozen while lowering the temperature in a stepwise fashion to -70 degrees C. After three weeks of cryogenic storage, the arteries were transplanted into Lewis andB.N. rats. At various times from the first to the twelfth week after surgery, grafted vessels were observed, and pathological and electron microscopic studies were carried out. The vessels were found to be in good condition at the end of the 12 week observation period. These results strongly suggest that prolonged cryopreservation of vessels makesallotransplantation without immunosuppression possible. (C) Wiley-Liss, Inc.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 15:33:38