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Titolo:
N-MYC EXPRESSION IN THE EMBRYONIC COCHLEA OF THE MOUSE
Autore:
ROMAND R; HIRNINGFOLZ U; EHRET G;
Indirizzi:
UNIV BLAISE PASCAL CLERMONT II,NEUROBIOL & PHYSIOL DEV LAB F-63177 CLERMONT FERRAND FRANCE UNIV ULM,KLIN GENET ABT W-7900 ULM GERMANY UNIV ULM,VERGLEICHEND NEUROBIOL ABT ULM GERMANY
Titolo Testata:
Hearing research
fascicolo: 1-2, volume: 72, anno: 1994,
pagine: 53 - 58
SICI:
0378-5955(1994)72:1-2<53:NEITEC>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
C-MYC; DIFFERENTIAL EXPRESSION; INSITU HYBRIDIZATION; GENE-EXPRESSION; MESSENGER-RNAS; INNER-EAR; ORGANOGENESIS; ONCOGENE; PROTEIN; CELLS;
Keywords:
N-MYC; PROTOONCOGENE; INNER EAR; ONTOGENY; SPIRAL GANGLION; KOLLIKERS ORGAN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
R. Romand et al., "N-MYC EXPRESSION IN THE EMBRYONIC COCHLEA OF THE MOUSE", Hearing research, 72(1-2), 1994, pp. 53-58

Abstract

N-myc expression in the mouse embryo was examined during the late cochlear organogenesis. Tissue distribution of N-myc expression was histologically analyzed by in situ hybridization of the transcript in the cochlea between 15 and 18 days of gestation. At 15 days of gestation, N-myc expression was found very conspicuous in nervous structure of thecochlea such as the auditory nerve and the spiral ganglion. Moreover,N-myc was also present in the Kollikers organ and in the epithelium surrounding the cochlear canal. A few days later, N-myc expression was still clearly present in the Kollikers organ but less so in nervous structures. This study shows that cochlear tissues derived from the oticplacode present a significant level of N-myc transcript during late embryogenesis. N-myc expression seems to be related to cell differentiation in the inner ear.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 10:00:14