Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CHOLINE-ACETYLTRANSFERASE IMMUNOREACTIVE COCHLEAR EFFERENT NEURONS INTHE CHICK AUDITORY BRAIN-STEM
Autore:
CODE RA; CARR CE;
Indirizzi:
UNIV MARYLAND,DEPT ZOOL COLL PK MD 20742
Titolo Testata:
Journal of comparative neurology
fascicolo: 2, volume: 340, anno: 1994,
pagine: 161 - 173
SICI:
0021-9967(1994)340:2<161:CICENI>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
GUINEA-PIG COCHLEA; BASILAR PAPILLA; BARN OWL; GLUTAMATE-DECARBOXYLASE; OLIVOCOCHLEAR NEURONS; NUCLEUS LAMINARIS; DEXTRAN-AMINES; ORGAN; CORTI; STEM;
Keywords:
EFFERENTS; OLIVOCOCHLEAR; CHOLINE ACETYLTRANSFERASE; DOUBLE LABELING; CHOLINERGIC;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
53
Recensione:
Indirizzi per estratti:
Citazione:
R.A. Code e C.E. Carr, "CHOLINE-ACETYLTRANSFERASE IMMUNOREACTIVE COCHLEAR EFFERENT NEURONS INTHE CHICK AUDITORY BRAIN-STEM", Journal of comparative neurology, 340(2), 1994, pp. 161-173

Abstract

Cholinergic neurons in the chick auditory brainstem were studied withthe aid of an antiserum to choline acetyltransferase (ChAT), the biosynthetic enzyme for acetylcholine. ChAT-immunoreactive (ChAT-I) neurons were found in a ventrolateral and a dorsomedial cell group. The ventrolateral group is a rostrocaudally directed column of cells that surround the superior olive (SO), are ventromedial to the ventral facial nucleus (VIIv), and are lateral to the nucleus pontis lateralis (PL) asfar rostrally as the nucleus subceruleus ventralis. Cells in the dorsomedial group were found in the pontine reticular formation medial to the dorsal facial nucleus and lateral to the abducens nerve root. Occasionally, small ChAT-I cells were found in the crossed dorsal cochleartract and in the medial vestibular nucleus near the dorsal border of the caudal nucleus magnocellularis (NM). No ChAT-I neurons or fibers were observed in NM, nucleus angularis, nucleus laminaris, in the nuclei of the lateral lemniscus, or in the nucleus mesencephalicus lateralis pars dorsalis. To determine which cholinergic neurons project to thecochlea, a double-labeling technique was used combining ChAT-I and the retrograde transport of biotinylated dextran amine (BDA) from the inner ear. Double-labeled cells were found bilaterally in both the ventrolateral and dorsomedial cell groups, with the exception of large ChAT-I cells dorsal to the SO, which do not appear to project to the cochlea. Cholinergic cells that project to the cochlea were classified intothree morphological groups: multipolar, elongate, and round-to-oval. Both the ventrolateral and the dorsomedial cell groups appear to have a mixture of these different cell types. The average somal area of cholinergic cochlear efferents was 246 mu m(2). Only about 70% of the cochlear efferent neurons, however, are cholinergic. (C) 1994 Wiley-Liss,Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/10/20 alle ore 01:32:18