Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CHARACTERIZATION OF 4 SHORT TANDEM REPEAT LOCI (THO1, VWA31 A, CD4, AND TP53) IN NORTHERN PORTUGAL/
Autore:
AMORIM A; GUSMAO L; PRATA MJ; SILVA F; BESSA I;
Indirizzi:
UNIV OPORTO,FAC CIENCIAS,INST ANTROPOL,PRACA GOMES TEIXEIRA P-4050 OPORTO PORTUGAL UNIV OPORTO,INST PATOL & IMUNOL MOL P-4050 OPORTO PORTUGAL
Titolo Testata:
Human biology
fascicolo: 1, volume: 69, anno: 1997,
pagine: 31 - 40
SICI:
0018-7143(1997)69:1<31:CO4STR>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
POPULATION-DATA; STR SYSTEMS; SPANISH POPULATION; MULTIPLEX PCR; HUMTHO1; POLYMORPHISM; GENE; IDENTIFICATION; HUMFES/FPS; HUMVWA;
Keywords:
PCR; STR; THO1; VWA31/A; TP53; CD4; POPULATION GENETICS; PORTUGAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
A. Amorim et al., "CHARACTERIZATION OF 4 SHORT TANDEM REPEAT LOCI (THO1, VWA31 A, CD4, AND TP53) IN NORTHERN PORTUGAL/", Human biology, 69(1), 1997, pp. 31-40

Abstract

Allele and genotype frequencies for two tetrameric and two pentamericshort tandem repeat (STR) loci (THO1, VWA31/A, CD4, and TP53) were determined in a population sample from northern Portugal. Genotyping of PCR amplification products was done using polyacrylamide gel electrophoresis followed by silver staining; heteroduplex analysis was performed to distinguish THO1 genotypes involving allele 10 and the nonconsensus allele 9.3. For all loci allele frequencies fitted the distributionpatterns generally observed in European populations, The observed genotype distributions do not deviate significantly from Hardy-Weinberg expectations, although for VWA31/A a significant excess of heterozygotes involving allele 17 was found. Mother-child pair analyses confirmed the regular Mendelian pattern of inheritance, Because the information content of these systems is high and because their genotyping is technically reliable and simple, CD4, THO1, VWA31/A, and TP53 are appropriate genetic systems for anthropological genetics.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 10:13:42