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Titolo:
INHIBITION BY IOTA-CARRAGEENAN OF THE SPREAD OF MURINE CYTOMEGALOVIRUS FROM THE PERITONEAL-CAVITY TO THE BLOOD-PLASMA
Autore:
HAMASUNA R; EIZURU Y; MINAMISHIMA Y;
Indirizzi:
MIYAZAKI MED COLL,DEPT MICROBIOL MIYAZAKI 88916 JAPAN MIYAZAKI MED COLL,DEPT MICROBIOL MIYAZAKI 88916 JAPAN
Titolo Testata:
Journal of General Virology
, volume: 75, anno: 1994,
parte:, 1
pagine: 111 - 116
SICI:
0022-1317(1994)75:<111:IBIOTS>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
BIOLOGICAL RESPONSE MODIFIERS; INFECTION; VIRUS; MICE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
R. Hamasuna et al., "INHIBITION BY IOTA-CARRAGEENAN OF THE SPREAD OF MURINE CYTOMEGALOVIRUS FROM THE PERITONEAL-CAVITY TO THE BLOOD-PLASMA", Journal of General Virology, 75, 1994, pp. 111-116

Abstract

The mechanism of iota-carrageenan (iota-CAR)-induced protection against murine cytomegalovirus (MCMV) infection of mice was analysed. The virus titres in the target organs on the fourth day correlated with that in the plasma at Ih after intraperitoneal inoculation of MCMV, irrespective of E-CAR treatment. Pretreatment of mice with I-CAR induced infiltration of polymorphonuclear neutrophils into the peritoneal cavityand inhibition of viral spread from the peritoneal cavity to the plasma. Although the direct relationship of these two phenomena was unclear, the inhibition by iota-CAR of viral spread resulted in protection against MCMV infection of mice.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 20:35:19