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Titolo:
USE OF PSYCHOTROPIC-DRUGS DURING PREGNANCY - A REPORT OF THE INTERNATIONAL COOPERATIVE DRUG-USE IN PREGNANCY (DUP) STUDY
Autore:
MARCHETTI F; ROMERO M; BONATI M; TOGNONI G; BONATI M; TOGNONI G; MIGLIO D; NIGRO M; BALOCCO R; BORTOLUS R; DAPSY I; MARCHETTI F; ROMERO M; COLOMBO F; FELLIN G; MARFISI RM; NEGRELLO I; OLIVIERI M; BATISTA MDDD; SATO A; BARROS JCR; LEONE CR; CURY M; ZULLINI MT; MATERASSI P; KLOTZEL D; PEREIRA JCR; GANDOLFI E; CARVALHO ML; PEREIRA VLM; MARETTI M; ESCALER MM; LIPPI UG; ARNAZI PV; CASANOVA LD; BATISTA NA; GARCIA SL; DEFREITAS E; GIANATTASIO F; ALMEIDA ACD; COSTA MF; SADECK LDR; RIVOREDO CR; MATAMOROS AC; CULIG J; KRISKA M; HRKOVA V; MRAZEK M; NOVARIK J; BLAAKAER J; PHILIP J; OBEL E; HEMMINKI E; HOFFMANNTRAEGER A; TEICHERT B; PEIKER G; REIMANN I; JAGER O; OFORIADJEI D; THOMAS M; UPPAL R; OHERLIHY C; COLLE G; FAILLI C; LINCIANO M; COMOTTI S; LEIDI G; ANTONINI E; PIZZURRO V; VECCHIONE A; BASEVI V; CAPOZZI A; CRESCINI C; AGOSTI S; CORRAO G; QUARANTA S; RAVASI L; RUSPI G; SPINA GF; VIGNATI A; PELLINI M; LONDERO F; ORTI CD; BORSATTO M; BRIGATO G; GRELLA P; CELLANI F; GROSSI F; TUDISCO A; PALMERIO G; STEVENAZZI G; TOMASSI A; MASSOBRIO M; MENATO G; ZAMBELLI G; PINTO P; BRESSAN G; CARLINO A; COLOMBO PA; MIGLIETTA P; ROSSI V; MARTINELLI P; DILAZZARO A; BERTULETTI P; CAVADINI R; LOMBARDI PL; DESENA C; MARSONI V; DELFAVERO A; VENTURA F; NARDUCCI U; AZZALINI B; PINTO A; PETRELLI A; LUERTI M; FANELLI A; MARIUCCI A; COLAVITA D; CUCCHIA G; MARGIACCHI P; MARCHETTI S; ANGIOLILLO M; GENTILE E; CESARATTO A; DANDREA O; DIPASQUALE R; ANGELI G; SETTONCE S; ORMANDO A; ZELANTE L; PICCOTTO G; TORRIOLI D; PAPA E; PALOMBARO G; MASCELLANTI P; DIFRANCESCO A; LOREFICE R; ANGELONI C; DECAROLIS AM; BALUCANI M; DAURIZIO MD; PETRICONE G; TATA R; LICATA F; TAMBURINI M; SELVA S; CALDERALE L; RIGONI I; STELLA G; RADAELLI R; PASSERELLI G; ALBONI A; SANTARELLI P; IEZZI E; PONTE B; DEMATTIA A; LANZASILVERI C; YOSHIOKA H; SHIMIZU T; FUJITA K; KAKUYA F; ITO S; NAMBU H; IWASAKI K; TAKEDA Y; AKERA T; KANEKO K; MASUMURA C; SEKI E; MUKUBO M; MATSUDA I; TSUNAWAKI T; KIYOTA Y; MIYAZAKI Y; IKENOUE T; NAKAYAMA M; INAFUKU Y; VENTURA CS; GRECH ES; HARDEN H; MATHESON I; BERGSJO P; PEEN A; NESHEIM BI; LEE D; STANULOVIC M; SABO A; DIOGENE E; LAPORTE JR; ARAGON C; VIDAL X; FARRE M; LLORENTE M; CASES CG; MARTI A; GRAU C; PALMA C; MARTINEZ J; ROMERO AS; SANCHEZ CF; NOGUES J; NOTIVOL R; SALVA R; MOTA C; MORILLAS MG; LAFUENTE L; ORTIZ J; ARENILLAS MG; DELOLMO TM; LOPO CR; FRIAS J; LUCENA MI; RIVERA RR; TRISTAN C; HONORATO J; SACRISTAN JA; MEDIAVILLA A; TORELLO J; SERRANO MI; HERNANDEZ JAG; OCON L; CUENA R; DEVELASCO JMG; HERNANDEZ G; ESPLUGUES J; SINUES B; MEMBRADO J; WEERASINGHE T; FERNANDO G; SODERMAN P; BLOMQVIST KH; DEJONGVANDEBERG L; WAARDENBURG M; BENNETT P; GRANT A; REID W; JACKSON A; MCGARRY JA; MCLEAN MW; HULSE M; CAMERON S; DUFFY S; VINALL P; BIBBY J; ELLIOT B; DEXTER J; USHERWOOD M; TEBBUTT H; BLIGH GM; KILLICK S; HIRSCH P; WINGFIELD W; BOBER SA; BULLOUGH C; HALL M; FISHER A; KASILO O; NYAZEMA N;
Indirizzi:
CONSORZIO MARIO NEGRI SUD,CLIN PHARMACOL & EPIDEMIOL LAB I-66030 SANTA MARIA IMBAR ITALY MARIO NEGRI INST PHARMACOL RES,MOTHER & CHILD HLTH LAB I-20157 MILAN ITALY
Titolo Testata:
European Journal of Clinical Pharmacology
fascicolo: 6, volume: 45, anno: 1993,
pagine: 495 - 501
SICI:
0031-6970(1993)45:6<495:UOPDP->2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
BENZODIAZEPINES INUTERO; EXPOSURE; DEPENDENCE; DIAZEPAM; CHILDREN; WOMEN; FETUS; RISKS;
Keywords:
PREGNANCY METHODOLOGICAL; PSYCHOTROPIC DRUGS; DRUG UTILIZATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
F. Marchetti et al., "USE OF PSYCHOTROPIC-DRUGS DURING PREGNANCY - A REPORT OF THE INTERNATIONAL COOPERATIVE DRUG-USE IN PREGNANCY (DUP) STUDY", European Journal of Clinical Pharmacology, 45(6), 1993, pp. 495-501

Abstract

Drug Use in Pregnancy (DUP) is an international epidemiological survey of drug use in pregnancy conducted from 1988 to 1990 in 148 maternity wards, representing the general delivery practices of 22 countries. Data on exposure of pregnant women to psychotropic drugs, the indications for their use and their correlation with maternal characteristics are reported. Of the 14,778 women interviewed, 520 (3.5%) reported 562courses of psychotropic drugs. Benzodiazepines (BDZ) accounted for the greatest number of the exposures (444/520 women); neuroleptics and antidepressants were prescribed to tiny minorities of women (83 and 17 respectively), mostly in those few countries were the overall prevalence of use of those drugs was highest. Throughout the majority of the other countries, overall rates were in the low range and were rather heterogeneous. With the exception of small clusters of ''unexpected'' indications, prescriptions of BDZ were found to be consistent with the target symptoms of anxiety and insomnia; chronic use was reported in 31/444 women. The study was not targeted to the detection of malformations; no suspected clustering was found, however, among the 130 women exposed during the first trimester of pregnancy. The collaborative network now established provides a framework for periodically replicated surveillance to monitor the evolution of this field of knowledge and care in order to provide reliable information for women and society.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 14:08:37