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Titolo:
THE DETECTION OF NUCLEOTIDE-SEQUENCES WITH STRONG SIMILARITY TO HORMONE-RESPONSIVE ELEMENTS IN THE GENOME OF EUBACTERIA AND ARCHAEBACTERIA AND THEIR POSSIBLE RELATION TO SIMILAR SEQUENCES PRESENT IN THE MITOCHONDRIAL GENOME
Autore:
HATZOGLOU E; SEKERIS CE;
Indirizzi:
UNIV ATHENS,DEPT BIOL GR-15701 ATHENS GREECE NATL HELLEN RES FDN,INST BIOL RES & BIOTECHNOL ATHENS GREECE UNIV ATHENS,SCH MED,BIOL CHEM LAB GR-11527 ATHENS GREECE
Titolo Testata:
Journal of theoretical biology
fascicolo: 3, volume: 184, anno: 1997,
pagine: 339 - 344
SICI:
0022-5193(1997)184:3<339:TDONWS>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
LACTIS SUBSP LACTIS; VIBRIO-CHOLERAE; RAT-LIVER; TRANSCRIPTIONAL ACTIVATORS; GLUCOCORTICOID RECEPTOR; RIBONUCLEIC-ACID; THYROID-HORMONE; RNA-SYNTHESIS; ARAC FAMILY; GENE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
E. Hatzoglou e C.E. Sekeris, "THE DETECTION OF NUCLEOTIDE-SEQUENCES WITH STRONG SIMILARITY TO HORMONE-RESPONSIVE ELEMENTS IN THE GENOME OF EUBACTERIA AND ARCHAEBACTERIA AND THEIR POSSIBLE RELATION TO SIMILAR SEQUENCES PRESENT IN THE MITOCHONDRIAL GENOME", Journal of theoretical biology, 184(3), 1997, pp. 339-344

Abstract

To account for the presence of nucleotide sequences in mitochondria with similarity to the Hormone Response Elements (HREs) of the nuclear genomes of man, rat and mouse, the genomes of several procaryotes havebeen screened for the presence of the sequences AGAACA NNN TGTTCT andGGTACA NNN TGTTCT, which represent perfect palindromic and consensus class I HREs, respectively, and for the sequence AGGTCA NNN TGACCT, which represents class II HRE. In many of the examined procaryotes, eubacteria and archaebacteria, almost perfect palindromic class I HREs andperfect or almost perfect class II half palindromic HREs have been detected in various genes, some of which encode proteins involved in energy metabolism, in replication and in transcription control. These findings support the hypothesis that the similar sequences found in mitochondria, potentially involved in hormonal regulation of respiratory enzyme biosynthesis, were introduced into eucaryotic cell by the procaryotic endosymbionts. (C) 1997 Academic Press Limited.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 02:00:27