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Titolo:
LACK OF ASSOCIATION OF ANGIOTENSIN I-CONVERTING ENZYME GENE POLYMORPHISM AND PREMATURE MYOCARDIAL-INFARCTION IN MAURITIAN INDIANS
Autore:
RAMASAWMY R; MANRAJ M; KOTEA N; SHUN NK; GENIN E; FEINGOLD J; KRISHNAMOORTHY R; BALIGADOO S;
Indirizzi:
HOP ROBERT DEBRE,INSERM U120,48 BD SERURIER F-75019 PARIS FRANCE SSR CTR MED RES MOKA MAURITIUS INSERM U155 PARIS FRANCE
Titolo Testata:
Clinical genetics
fascicolo: 6, volume: 50, anno: 1996,
pagine: 551 - 554
SICI:
0009-9163(1996)50:6<551:LOAOAI>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; DELETION POLYMORPHISM; RISK FACTOR; CARDIOMYOPATHY;
Keywords:
ANGIOTENSIN I-CONVERTING ENZYME; DNA; MAURITIAN INDIANS; POLYMORPHISM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
R. Ramasawmy et al., "LACK OF ASSOCIATION OF ANGIOTENSIN I-CONVERTING ENZYME GENE POLYMORPHISM AND PREMATURE MYOCARDIAL-INFARCTION IN MAURITIAN INDIANS", Clinical genetics, 50(6), 1996, pp. 551-554

Abstract

Eighty-five young Mauritian Indians, male survivors of premature myocardial infarction (MI) and thus belonging to a high risk group, were compared with 108 stringently selected controls for a possible association between premature MI and an insertion/deletion (I/D) polymorphism in the gene encoding angiotensin I-converting enzyme (ACE). The frequency of the D allele was 0.42 in the MI group and 0.43 in the control group, and thus no association between I/D polymorphism of ACE with susceptibility to early-onset MI was found in this population group. Other gene components of the renin-angiotensin system and lipid metabolismneed to be explored to understand the genetic factors involved in causing MI at an early age.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/06/20 alle ore 00:53:31