Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
AORTIC COMPLIANCE MEASUREMENTS USING DOPPLER ULTRASOUND - IN-VIVO BIOCHEMICAL CORRELATES
Autore:
LEHMANN ED; HOPKINS KD; GOSLING RG;
Indirizzi:
UNITED MED & DENT SCH GUYS & ST THOMAS HOSP,ST THOMAS HOSP,DEPT ENDOCRINOL & CHEM PATHOL LONDON SE1 7EH ENGLAND UNIV LONDON,UNITED MED & DENT SCH GUYS & ST THOMAS HOSP,DIV RADIOL SCI LONDON ENGLAND UNIV LONDON,UNITED MED & DENT SCH GUYS & ST THOMAS HOSP,DIV CHEM PATHOL LONDON ENGLAND UNIV LONDON,UNITED MED & DENT SCH GUYS & ST THOMAS HOSP,DIV MED LONDON ENGLAND
Titolo Testata:
Ultrasound in medicine & biology
fascicolo: 9, volume: 19, anno: 1993,
pagine: 683 - 710
SICI:
0301-5629(1993)19:9<683:ACMUDU>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
GROWTH FACTOR-I; PULSE-WAVE VELOCITY; SMOOTH-MUSCLE CELLS; CORONARY-ARTERY DISEASE; RAT AORTA; ATHEROSCLEROSIS PROGRESSION; CARDIOVASCULAR-DISEASE; BALLOON DENUDATION; DIABETES-MELLITUS; MESSENGER-RNA;
Keywords:
DOPPLER ULTRASOUND; AORTIC COMPLIANCE; ARTERIAL DISTENSIBILITY; ELASTICITY; STIFFNESS; PULSE WAVE VELOCITY; BLOOD PRESSURE; REPRODUCIBILITY; LIPIDS; GROWTH FACTORS; DIABETES-MELLITUS; FAMILIAL HYPERCHOLESTEROLEMIA; GROWTH HORMONE; ATHEROSCLEROSIS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
106
Recensione:
Indirizzi per estratti:
Citazione:
E.D. Lehmann et al., "AORTIC COMPLIANCE MEASUREMENTS USING DOPPLER ULTRASOUND - IN-VIVO BIOCHEMICAL CORRELATES", Ultrasound in medicine & biology, 19(9), 1993, pp. 683-710

Abstract

A noninvasive Doppler ultrasound technique for the assessment of aortic compliance based on the in vivo measurement of pulse wave velocity along the thoraco-abdominal aortic pathway is described. An approach for correcting for the effect of blood pressure on aortic distensibility is considered. The derivation of an index of intrinsic distensibility, Cp, which is independent of blood pressure, is provided and appliedto data collected from normal, healthy volunteers. Overviews are provided of studies utilising the technique to determine aortic compliancein medical disorders, which are known to predispose to premature cardiovascular disease, such as diabetes mellitus, familial hypercholesterolaemia and growth hormone deficiency. The significance of correlations between in vivo aortic compliance measurements and plasma concentrations of total cholesterol, low-density-lipoprotein cholesterol, high-density-lipoprotein cholesterol and insulin-like growth factor-I are discussed. It is proposed that the measurement of aortic compliance in normal, healthy individuals may potentially be a useful in vivo research tool for investigating the effects of biochemical factors on the biophysical properties of the aortic wall. Furthermore, we believe that the routine measurement of blood pressure-corrected aortic distensibility may prove a useful, noninvasive clinical tool for assessing patients' susceptibility to atherosclerosis, as well as for monitoring their response to therapeutic interventions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 13:51:55