Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CLINICAL SPECTRUM OF THE TOMACULOUS NEUROPATHIES - REPORT OF 60 CASESAND REVIEW OF THE LITERATURE
Autore:
RIZZUTO N; MORETTO G; GALIAZZO RS;
Indirizzi:
UNIV VERONA,POLICLIN BORGO ROMA,IST NEUROL I-37134 VERONA ITALY
Titolo Testata:
Italian journal of neurological sciences
fascicolo: 9, volume: 14, anno: 1993,
pagine: 609 - 617
SICI:
0392-0461(1993)14:9<609:CSOTTN>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRESSURE-SENSITIVE NEUROPATHY; RECURRENT FAMILIAL NEUROPATHY; IGM MONOCLONAL GAMMOPATHY; MARIE-TOOTH DISEASE; BRACHIAL-PLEXUS; HEREDITARY NEUROPATHY; PERIPHERAL NEUROPATHY; PALSIES; LIABILITY; NERVE;
Keywords:
PERIPHERAL NERVE; TOMACULOUS CHANGES; HEREDITARY NEUROPATHY; PRESSURE SENSITIVE NEUROPATHY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
N. Rizzuto et al., "CLINICAL SPECTRUM OF THE TOMACULOUS NEUROPATHIES - REPORT OF 60 CASESAND REVIEW OF THE LITERATURE", Italian journal of neurological sciences, 14(9), 1993, pp. 609-617

Abstract

Tomaculous neuropathy has a distinctive pathological pattern of myelin thickenings in a high proportion of internodes but no specific pattern of nerve degeneration. We have analyzed the variable clinical expression of this disorder in a large series of patients. Different phenotypes have been recognized. the majority of our patients (52 cases) hadhereditary neuropathy with liability to pressure palsy (HNPP) showingwide variability of clinical progression and of severity of the single episodes. 3 patients suffered from familial recurrent brachial plexus neuropathy (FBPN); 5 patients had a symmetrical progressive sensorimotor involvement of the limbs (SSMN), predominantly in the distal portions and leading to permanent disability. The explanation for this clinical variability does not emerge from our data or from the literature. Segmental demyelination is the major change correlating with the episodes of nerve palsy; axonal degeneration might be rarely associated. The myelin sausages are the markers of a selective vulnerability of the nerve fibers either to mechanical injury or to some other unknown event.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 14:17:23