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Titolo:
NUCLEUS BASALIS MAGNOCELLULARIS AND ATTENTION - EFFECTS OF MUSCIMOL INFUSIONS
Autore:
PANG K; WILLIAMS MJ; EGETH H; OLTON DS;
Indirizzi:
UNIFORMED SERV UNIV HLTH SCI,DEPT PHARMACOL,4301 JONES BRIDGE RD BETHESDA MD 20814 JOHNS HOPKINS UNIV,DEPT PSYCHOL BALTIMORE MD 21218
Titolo Testata:
Behavioral neuroscience
fascicolo: 6, volume: 107, anno: 1993,
pagine: 1031 - 1038
SICI:
0735-7044(1993)107:6<1031:NBMAA->2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHOLINERGIC SYSTEMS; MEDIAL SEPTUM; FOREBRAIN; NEURONS; LESIONS; MECHANISMS; BRAIN; RATS; TASK;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
K. Pang et al., "NUCLEUS BASALIS MAGNOCELLULARIS AND ATTENTION - EFFECTS OF MUSCIMOL INFUSIONS", Behavioral neuroscience, 107(6), 1993, pp. 1031-1038

Abstract

The basal forebrain is important in cognitive processing. Most studies have focused on the importance of this area in mnemonic processing. However, the nucleus basalis magnocellularis (NBM), which is a major component of the basal forebrain, may also be involved in attentional processes. Attention can influence the sensitivity of perceptual processes, as assessed by discriminability, or the selection of response strategies, as assessed by bias. This experiment examined whether temporary inactivation of the NBM, using the GABA agonist muscimol, would interfere with attention. Each rat was tested in a 2-choice reaction time(RT) task in which stimulus frequency was varied. RT and error rate increased, and discriminability decreased following muscimol infusions into the NBM. Bias was unchanged. The pattern of results provides evidence that the NBM is important in attention, and this influence of theNBM acts primarily on perceptual aspects of attention.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 07:26:55