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Titolo:
MENOPAUSAL STATUS INFLUENCES AMBULATORY BLOOD-PRESSURE LEVELS AND BLOOD-PRESSURE CHANGES DURING MENTAL STRESS
Autore:
OWENS JF; STONEY CM; MATTHEWS KA;
Indirizzi:
UNIV PITTSBURGH,SCH MED,DEPT PSYCHIAT,3811 OHARA ST PITTSBURGH PA 15213 BROWN UNIV,MIRIAM HOSP PROVIDENCE RI 00000
Titolo Testata:
Circulation
fascicolo: 6, volume: 88, anno: 1993,
pagine: 2794 - 2802
SICI:
0009-7322(1993)88:6<2794:MSIABL>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; DENSITY LIPOPROTEIN CHOLESTEROL; NEURO-ENDOCRINE RESPONSES; TOTAL SERUM-CHOLESTEROL; SEX-DIFFERENCES; BEHAVIORAL STRESS; WOMEN; RISK; REACTIVITY; TRIGLYCERIDES;
Keywords:
RISK FACTORS; WOMEN; CATECHOLAMINES; BLOOD PRESSURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
J.F. Owens et al., "MENOPAUSAL STATUS INFLUENCES AMBULATORY BLOOD-PRESSURE LEVELS AND BLOOD-PRESSURE CHANGES DURING MENTAL STRESS", Circulation, 88(6), 1993, pp. 2794-2802

Abstract

Background. Frequent and large cardiovascular and neuroendocrine responses to psychological stress are thought to enhance an individual's risk for cardiovascular diseases. Preliminary data suggest that levels of reproductive hormones affect the magnitude of stress responses, perhaps contributing to the protective effect of ovarian hormones on premenopausal women's rates of coronary heart disease. Methods and Results. Healthy middle-aged men and premenopausal and postmenopausal women performed a series of standardized mental and physical challenges whileblood pressure, heart rate, plasma catecholamines, lipids, and lipoproteins were measured. Subjects then wore an ambulatory blood pressure monitor during two consecutive workdays. Results showed that postmenopausal women had larger mean+/-SEM stress-induced increases in systolicblood pressure (24.7+/-2.2 mm Hg) and diastolic blood pressure (14.3+/-1.0 mm Hg) compared with either premenopausal women (16.9+/-1.3 and 10.2+/-0.9 mm Hg) or men (17.7+/-1.5 and 10.9+/-1.1 mm Hg, respectively). Postmenopausal women and men had higher mean+/-SEM ambulatory diastolic blood pressure levels (75.5+/-3.2 and 76.4+/-1.8 mm Hg) than didpremenopausal women (69.9+/-2.2 mm Hg). Large blood pressure responses during public speaking were associated with high cholesterol levels and low educational attainment. Conclusions. Menopause is associated with enhanced stress-induced cardiovascular responses and elevated ambulatory blood pressure during the workday. These effects may contributeto the risk of cardiovascular morbidity and mortality after the menopause.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 10:12:50