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Titolo:
MURAL NODULES IN COMMON EPITHELIAL TUMORS OF THE OVARY
Autore:
BAERGEN RN; RUTGERS JL;
Indirizzi:
UCSD,SCH MED,MED CTR,DEPT PATHOL,200 W ARBOR DR SAN DIEGO CA 92103 UCLA,HARBOR MED CTR LOS ANGELES CA 00000
Titolo Testata:
International journal of gynecological pathology
fascicolo: 1, volume: 13, anno: 1994,
pagine: 62 - 72
SICI:
0277-1691(1994)13:1<62:MNICET>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
MUCINOUS CYSTADENOCARCINOMA; ANAPLASTIC CARCINOMA; SARCOMA; DERIVATION;
Keywords:
MURAL NODULES; EPITHELIAL TUMORS; OVARIAN SARCOMAS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
R.N. Baergen e J.L. Rutgers, "MURAL NODULES IN COMMON EPITHELIAL TUMORS OF THE OVARY", International journal of gynecological pathology, 13(1), 1994, pp. 62-72

Abstract

The occurrence of mural nodules in cystic common epithelial tumors ofthe ovary is well established, but differences in terminology and difficulties in histopathologic interpretation have hampered adequate understanding of their differential diagnoses and prognoses. Using immunohistochemistry and ultrastructural analyses supplementally, we studiedtwo cases, one a serous cystadenocarcinoma with nodules of undifferentiated sarcoma, the other a mucinous cystadenocarcinoma with mural nodules of anaplastic carcinoma. Based on these cases and a review of 48 cases in the literature, we propose a standardized terminology. Mural nodules may be either reactive or neoplastic. Neoplastic mural nodulesmay be composed of benign elements, carcinoma, carcinoma with reactive elements, sarcoma, or an admixture of carcinoma and sarcoma; the latter category has some similarities to malignant mixed mesodermal tumors. The prognosis of patients with malignant mural nodules is poor, with 50% mortality. Strict morphologic criteria supplemented by immunohistochemistry aids in the sometimes difficult differential diagnosis among these types of mural nodules.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 07:35:32