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Titolo:
ACE-INHIBITORS IN RENAL REPLACEMENT THERA PY
Autore:
WARNEKE G; VONPAPPENHEIM G; FIEDLER M;
Indirizzi:
STEFFENSWEG 99 D-37120 BOVENDEN GERMANY DIALYSEZENTRUM GOTTINGEN GERMANY
Titolo Testata:
Nieren- und Hochdruckkrankheiten
fascicolo: 1, volume: 26, anno: 1997,
pagine: 34 - 38
SICI:
0300-5224(1997)26:1<34:AIRRTP>2.0.ZU;2-A
Fonte:
ISI
Lingua:
GER
Soggetto:
CONVERTING-ENZYME-INHIBITORS; FLUX MEMBRANE DIALYSIS; ANAPHYLACTOID REACTIONS;
Keywords:
ACE INHIBITOR; ANAPHYLACTIC REACTION; ANGIOTENSIN CONVERTING ENZYME (ACE); DIALYSIS MEMBRANE; HEMODIAFILTRATION (HDF); HEMODIALYSIS (HD); HEMOFILTRATION (HF); KIDNEY REPLACEMENT THERAPY; RENAL INSUFFICIENCY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
G. Warneke et al., "ACE-INHIBITORS IN RENAL REPLACEMENT THERA PY", Nieren- und Hochdruckkrankheiten, 26(1), 1997, pp. 34-38

Abstract

Administration of ACE inhibitors and simultaneous use especially of high-flux membranes, however also of low-flux membranes, may occasionally lead to anaphylactoid reactions. This is attributed to bradykinin accumulation. The goal of this retrospective study was the recording ofside effects under ACE inhibitor therapy with dialysis patients. From58 dialysis centers selected at random in the old federal countries of the FRG 3,006 dossiers of dialysis patients have been evaluated and side effects from a period of 22 month registered. 934 out of 3,006 (31,1%) dialysis patients have or had received an ACE inhibitor during the period investigated. With 163 of these 934 patients (17,5%) ACE inhibitor medication was discontinued later on. 122 patients (13,1%) showed a normotonic or lightly hypotonic circulatory status, 9 patients (1%) a lack of compliance and 32 patients (3,4%) a side effect related to the respective ACE inhibitor. With three cases (0,3%) an anaphylactoid reaction was obeserved during the initial phase of dialysis which had to be treated with corticosteroids. In two cases a polyacrplonitrile membrane and in one case a cuprophan membrane were used for dialysing. With one patient was switched over to another membrane type for thefollowing dialysis (before Pan, then Cu), ACE inhibtor therapy was maintained. With two patients ACE inhibitor administration was stopped, but the respective dialysis membrane used further on (Pan and Cu). In no case a reexposition was tried, there was no new event occurring under the modified modalities any more.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/01/21 alle ore 23:09:17