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Titolo:
VITAMIN-D DEFICIENCY - A CULPRIT IN METABOLIC BONE-DISEASE
Autore:
HOFELDT FD;
Indirizzi:
DENVER GEN HOSP,DEPT MED,777 BANNOCK ST,BOX 4000 DENVER CO 80204 UNIV COLORADO,HLTH SCI CTR DENVER CO 00000
Titolo Testata:
Progress in food and nutrition science
fascicolo: 4, volume: 17, anno: 1993,
pagine: 377 - 399
SICI:
0306-0632(1993)17:4<377:VD-ACI>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
LINKED HYPOPHOSPHATEMIC RICKETS; INTESTINAL CALCIUM-ABSORPTION; POST-MENOPAUSAL OSTEOPOROSIS; D-DEPENDENT RICKETS; D ENDOCRINE SYSTEM; POSTMENOPAUSAL OSTEOPOROSIS; PARATHYROID-HORMONE; SEASONAL-VARIATION; DIETARY CALCIUM; SERUM 1,25-DIHYDROXYVITAMIN-D;
Keywords:
VITAMIN-D METABOLISM; OSTEOMALACIA; OSTEOPOROSIS; AGING; VITAMIN DEFICIENCY; VITAMIN-D-RESISTANCE; HYPOVITAMINOSIS-D; VITAMIN-D OSTEOPATHY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
155
Recensione:
Indirizzi per estratti:
Citazione:
F.D. Hofeldt, "VITAMIN-D DEFICIENCY - A CULPRIT IN METABOLIC BONE-DISEASE", Progress in food and nutrition science, 17(4), 1993, pp. 377-399

Abstract

Bone formation and bone remodeling are complicated processes regulated by systemic hormones and paracrine factors which regulate calcium and phosphate fluxes and cellular differentiation. The many actions of vitamin D reinforces its importance in the process of growth, maturation and aging of bone. An understanding of these important regulators ofbone metabolism is important to understanding the clinical disorders as they are related to alterations in vitamin D metabolism and metabolic bone disease. Specific disorders of vitamin D metabolism can be related to clinical disease states of aging, altered lifestyles, gastrointestinal, renal and hepatic disease. A classification of altered vitamin D metabolism as related to its clinical states is presented. The scope of vitamin D deficiency from childhood rickets to adult osteomalacia and osteoporosis is presented, Intermediate syndromes of high turnover osteoporosis, subclinical vitamin D-deficiency states, role of vitamin D analogues in treating type I and type II osteoporosis is discussed. Treatment guidelines for managing this scope of clinical vitamin D disorders are provided.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 11:04:58