Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
THE ROLE OF THE COCHLEAR EFFERENT SYSTEM IN ACQUIRED-RESISTANCE TO NOISE-INDUCED HEARING-LOSS
Autore:
ZHENG XY; HENDERSON D; MCFADDEN SL; HU BH;
Indirizzi:
SUNY BUFFALO,HEARING RES LABS,DEPT COMMUNICAT DISORDERS & SCI,215 PARKER HALL BUFFALO NY 14214 SUNY BUFFALO,HEARING RES LABS,DEPT COMMUNICAT DISORDERS & SCI BUFFALONY 14214
Titolo Testata:
Hearing research
fascicolo: 1-2, volume: 104, anno: 1997,
pagine: 191 - 203
SICI:
0378-5955(1997)104:1-2<191:TROTCE>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
CROSSED OLIVOCOCHLEAR BUNDLE; ACOUSTIC-DISTORTION PRODUCTS; TEMPORARY THRESHOLD SHIFTS; GUINEA-PIG COCHLEA; MIDDLE-EAR MUSCLES; ELECTRICAL-STIMULATION; DE-EFFERENTATION; EXPOSURE; NEURONS; PROTECTION;
Keywords:
COCHLEAR INNERVATION; TOUGHENING; ACOUSTIC TRAUMA; HAIR CELL LOSS; HISTOCHEMISTRY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
X.Y. Zheng et al., "THE ROLE OF THE COCHLEAR EFFERENT SYSTEM IN ACQUIRED-RESISTANCE TO NOISE-INDUCED HEARING-LOSS", Hearing research, 104(1-2), 1997, pp. 191-203

Abstract

Previous work has shown that the cochlear efferent system may play a role in protecting the ear from noise-induced temporary threshold shifts (TTS) following exposures to a single tone or a series of moderate-level noises ('toughening'). However, whether the olivocochlear bundle(OCB) is important in decreasing noise-induced permanent threshold shifts (PTS) remains an open question. The importance of the OCB in decreasing the ear's susceptibility to noise, as reflected by 2f(1)-f(2) distortion product otoacoustic emissions, was assessed by sectioning both the ipsilateral and contralateral divisions of the efferent system and exposing chinchillas while awake to an octave band noise (4 kHz) at a low level (85 dB SPL) for 10 days (6 h/day) and then at a high level (95 dB SPL) for 48 h. Complete de-efferentation was verified by cochlear acetylcholinesterase staining. The ears that were de-efferented showed substantially more TTS, greater PTS and larger cochlear lesionsof outer hair cells. The results suggest that the efferent system mayinfluence the ear's ability to develop resistance to noise trauma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 19:35:38