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Titolo:
SURVEY OF ANTIMICROBIAL SUSCEPTIBILITY OF MODERATELY HALOPHILIC EUBACTERIA AND EXTREMELY HALOPHILIC AEROBIC ARCHAEOBACTERIA - UTILIZATION OF ANTIMICROBIAL RESISTANCE AS A GENETIC-MARKER
Autore:
NIETO JJ; FERNANDEZCASTILLO R; GARCIA MT; MELLADO E; VENTOSA A;
Indirizzi:
UNIV SEVILLA,FAC PHARM,DEPT MICROBIOL & PARASITOL E-41012 SEVILLE SPAIN
Titolo Testata:
Systematic and applied microbiology
fascicolo: 3, volume: 16, anno: 1993,
pagine: 352 - 360
SICI:
0723-2020(1993)16:3<352:SOASOM>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARCHAEBACTERIUM HALOBACTERIUM-VOLCANII; SHUTTLE VECTORS; GEN-NOV; HALOFERAX-MEDITERRANEI; NUMERICAL TAXONOMY; DNA-SYNTHESIS; TRANSFORMATION; PLASMID; HALOBIUM; SENSITIVITY;
Keywords:
ANTIMICROBIAL SUSCEPTIBILITY; MODERATELY HALOPHILIC EUBACTERIA; HALOBACTERIA; ANTIBIOTIC RESISTANT MUTANTS; GENETIC MARKERS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
J.J. Nieto et al., "SURVEY OF ANTIMICROBIAL SUSCEPTIBILITY OF MODERATELY HALOPHILIC EUBACTERIA AND EXTREMELY HALOPHILIC AEROBIC ARCHAEOBACTERIA - UTILIZATION OF ANTIMICROBIAL RESISTANCE AS A GENETIC-MARKER", Systematic and applied microbiology, 16(3), 1993, pp. 352-360

Abstract

The susceptibility patterns of 94 moderately halophilic eubacteria and 24 extremely halophilic archaeobacteria to 22 antimicrobials were surveyed by using an agar dilution method. The moderate halophiles included 16 culture collection strains and 78 fresh isolates, representatives of Vibrio costicola, Deleya halophila, Deleya salina, Volcaniella euryhalina, and Chromohalobacter marismortui. On the basis of their MICs, the moderately halophilic collection strains showed very heterogeneous responses to the majority of antimicrobials tested and especially to ampicillin, cephalotin, and penicillin G. However, they showed a similar high tolerance to amynoglycosides, spectinomycin, and sulfonamide, and a high sensitivity to rifampicin, which was the most active inhibitor. The responses of the fresh isolates were also very heterogeneous and, in general, different susceptibility patterns to those showed by the corresponding collection strains were found. A general sensitivity of the halobacteria towards anysomycin, aphidicolin, rifampicin, and to novobiocin was found. This latter antibiotic showed the highest toxicity since MIC values as low as 0.06 mu g/ml were obtained. In contrast, the response to the other antibiotics was very heterogeneous. The frequencies of spontaneous mutation of resistance to different antibiotics for some selected collection strains have been determined for genetic purposes. For moderate halophiles, optimal frequencies were found with respect to streptomycin, rifampicin and chloramphenicol. On the other hand, the resistances to anysomicin, josamycin, monensin, andrifampicin appeared as the most suitable for halobacteria.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 04:22:08