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Titolo:
ANTIOBESITY EFFECT OF CHOLEST-4-EN-3-ONE, AN INTESTINAL CATABOLITE OFCHOLESTEROL, ON MICE
Autore:
SUZUKI K;
Indirizzi:
INST PHYS & CHEM RES,ANIM & CELLULAR LAB WAKO SAITAMA 35101 JAPAN
Titolo Testata:
Journal of nutritional science and vitaminology
fascicolo: 5, volume: 39, anno: 1993,
pagine: 537 - 543
SICI:
0301-4800(1993)39:5<537:AEOCAI>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Keywords:
CHOLEST-4-EN-3-ONE (CHOLESTENONE); INTESTINAL CHOLESTEROL CATABOLITE; ANTIOBESITY (BODY-WEIGHT LOSS); ADIPOSE TISSUE; SERUM LIPIDS; LIPOPROTEIN; CDF1 MOUSE;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
K. Suzuki, "ANTIOBESITY EFFECT OF CHOLEST-4-EN-3-ONE, AN INTESTINAL CATABOLITE OFCHOLESTEROL, ON MICE", Journal of nutritional science and vitaminology, 39(5), 1993, pp. 537-543

Abstract

An anti-obesity effect was observed for cholest-4-en-3-one (cholestenone) which is an intestinal catabolite of cholesterol. Body weight gain and body fat accumulation of CDF1 mice were inhibited by 0.5% dietary exposure to this chemical. Dose response for the effect of cholestenone was found to increase as the dose rose from 0.1 to 0.3% and 0.5%. No obvious anomaly due to consumption of cholestenone was detected by necropsy and clinical observation. The mechanism of this effect of cholestenone is not known at present, but it was not due to anorexia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 18:30:26