Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CONCURRENT ACUTE EXERCISE ALTERS CENTRAL AND PERIPHERAL RESPONSES TO PHYSOSTIGMINE
Autore:
DUBE SN; SOMANI SM; BABU SR;
Indirizzi:
SO ILLINOIS UNIV,SCH MED,DEPT PHARMACOL,POB 19230 SPRINGFIELD IL 62794 SO ILLINOIS UNIV,SCH MED,DEPT PHARMACOL,POB 19230 SPRINGFIELD IL 62794 VET ADM MED CTR ST LOUIS MO 63125
Titolo Testata:
Pharmacology, biochemistry and behavior
fascicolo: 4, volume: 46, anno: 1993,
pagine: 827 - 834
SICI:
0091-3057(1993)46:4<827:CAEACA>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHOLINESTERASE ACTIVITY; RAT; PHARMACOKINETICS; TISSUES; SOMAN;
Keywords:
CHOLINESTERASE IN RBC AND TISSUES; CONCURRENT ACUTE EXERCISE; PHYSOSTIGMINE; RATE OF DECARBAMYLATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
S.N. Dube et al., "CONCURRENT ACUTE EXERCISE ALTERS CENTRAL AND PERIPHERAL RESPONSES TO PHYSOSTIGMINE", Pharmacology, biochemistry and behavior, 46(4), 1993, pp. 827-834

Abstract

This study reports the modulatory effects of physostigamine (Phy) andconcurrent acute exercise on the time course of cholinesterase (ChE) activity, the rate of decarbamylation (K(d)), and half-time of recovery of ChE in red blood cells (RBC) and various tissues of rats. Acute exercise equivalent to 80% VO2max (maximal oxygen consumption) transiently increased the RBC ChE activity, whereas Phy decreased ChE activityin RBC and various tissues. Physostigmine along with concurrent acuteexercise increased the K(d) in RBC, brain, and heart by 56.4%, 66.7%,and 139%, respectively, compared to Phy alone. The K(d) in diaphragm and muscle decreased to 14.1% and 56.2%, respectively, compared to Phyalone. The variation in K(d) might be due to the effect of concurrentacute exercise on the redistribution of Phy in various tissues of ratas a result of changes in blood flow.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/10/20 alle ore 03:43:20