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Titolo:
ABNORMAL PROPORTION OF GAMMA-DELTA T-CELLS IN PERIPHERAL-BLOOD IS FREQUENTLY DETECTED IN PATIENTS WITH PERIODONTAL-DISEASE
Autore:
NAGAI A; TAKAHASHI K; SATO N; MATSUO Y; MINOWADA J; KURIHARA H; MURAYAMA Y;
Indirizzi:
OKAYAMA UNIV,SCH DENT,DEPT PERIODONTOL & ENDODONTOL,2-5-1 SHIKATA CHOOKAYAMA OKAYAMA 700 JAPAN OKAYAMA UNIV,SCH DENT,DEPT PERIODONTOL & ENDODONTOL OKAYAMA OKAYAMA 700 JAPAN HAYASHIBARA BIOCHEM LABS INC,FUJISAKI CELL CTR OKAYAMA OKAYAMA JAPAN
Titolo Testata:
Journal of periodontology
fascicolo: 10, volume: 64, anno: 1993,
pagine: 963 - 967
SICI:
0022-3492(1993)64:10<963:APOGTI>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
RHEUMATOID-ARTHRITIS; LYMPHOCYTES BEARING; HIV-1 INFECTION; SYNOVIAL-FLUID; RECEPTOR; SUBSETS; EXPRESSION; EXPANSION; TISSUE;
Keywords:
PERIODONTITIS/IMMUNOLOGY; T-CELL; BLOOD/CYTOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
A. Nagai et al., "ABNORMAL PROPORTION OF GAMMA-DELTA T-CELLS IN PERIPHERAL-BLOOD IS FREQUENTLY DETECTED IN PATIENTS WITH PERIODONTAL-DISEASE", Journal of periodontology, 64(10), 1993, pp. 963-967

Abstract

THE PROPORTIONS OF gamma delta T CELLS IN the peripheral blood of 8 early-onset periodontitis (EOP) patients, 8 later-onset periodontitis (LOP) patients, and of 17 healthy subjects (HS) were assessed by immunofluorescence assay using an anti-pan gamma delta T cell monoclonal antibody (TCR-delta 1) to study the population attributes of peripheral blood gamma delta T cells in patients with periodontal disease. The distribution of the proportions of gamma delta T cells in both EOP and LOP patients was found to be one and one half times broader than that inthe HS; however, there was no significant difference in the proportion of gamma delta T cells between each group. An abnormally high proportion of peripheral blood gamma delta T cells in pan T cells (>9.90%) was observed in 37.5% of both the EOP patients and the LOP patients. Anabnormally low proportion (<5.57%) was observed in 50% of the EOP patients and in 25% of the LOP patients. The higher occurrences of the high or low gamma delta T cell proportions were significant between EOP and HS, and between EOP + LOP and HS. There was no correlation betweenthe proportion of gamma delta T cells and age or the clinical parameters of periodontal status. It was concluded that an abnormal proportion of gamma delta T cells is frequently detected in patients with periodontal disease. These findings are consistent with the proposed role of the gamma delta T cells for playing a unique role as a first line defense against infections at body surfaces.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 21:50:57