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Titolo:
THE VARIED OUTCOMES OF SCHIZOPHRENIA
Autore:
DAVIDSON L; MCGLASHAN TH;
Indirizzi:
YALE UNIV,SCH MED,DEPT PSYCHIAT,34 PK ST NEW HAVEN CT 06519 CONNECTICUT MENTAL HLTH CTR,PSYCHOSIS PROGRAM NEW HAVEN CT 00000 YALE PSYCHIAT INST NEW HAVEN CT 00000
Titolo Testata:
Canadian journal of psychiatry
fascicolo: 1, volume: 42, anno: 1997,
pagine: 34 - 43
SICI:
0706-7437(1997)42:1<34:TVOOS>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
LONG-TERM COURSE; RECENT-ONSET SCHIZOPHRENIA; SERIOUS MENTAL-ILLNESS; FOLLOW-UP; SUBSTANCE-ABUSE; 1ST-EPISODE SCHIZOPHRENIA; GENDER DIFFERENCES; NEGATIVE SYMPTOMS; EDITORS INTRODUCTION; INTERNATIONAL PILOT;
Keywords:
FOLLOW-UP STUDIES; PRODROME; ONSET HETEROGENEITY; OUTCOME; DURATION OF UNTREATED PSYCHOSIS; NEGATIVE SYMPTOMS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
118
Recensione:
Indirizzi per estratti:
Citazione:
L. Davidson e T.H. Mcglashan, "THE VARIED OUTCOMES OF SCHIZOPHRENIA", Canadian journal of psychiatry, 42(1), 1997, pp. 34-43

Abstract

Objective: To review variations in outcomes in schizophrenia across individual, historical, and cross-cultural boundaries, as well as within specific domains of functioning. Method: Research literature on the outcomes of schizophrenia appearing within the last 8 years was reviewed. Results: First, a review of follow-up studies published in the developed world suggests that heterogeneity in outcome across individualswith schizophrenia remains the rule, with affective symptoms, later and acute onset and responsiveness to biological treatments predictive of good outcome. Negative symptoms are associated with poor outcome cognitive impairments, and incapacity in social and,cork domains. Deterioration appears to occur within the first few months of onset if not already in the prodrome, with recent early-course studies finding longer duration of untreated psychosis associated with insidious onset, negative symptoms, social and work incapacity, and poor outcome Second, areview, of recent cross-cultural and historical studies provides evidence that outcome I-caries across time and place, schizophrenia havinga more favourable outcome in the developing world and becoming a morebenign disorder over the course of this century Third, a review of studies of the domains of functioning within individuals identifies 4 relatively independent dimensions of depression and negative, psychotic,and disorganized symptoms. Cognitive deficits, which are associated with negative symptoms, also constitute a relatively stable dimension over time, showing neither marked deterioration nor improvement once established early in the course of disorder. Conclusions: The early appearance and stability over time of negative symptoms and cognitive impairments call for assertive intervention efforts early in the course ofdisorder to prevent chronicity and prolonged disability.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 07:32:57