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Titolo:
EXTRAPYRAMIDAL MOTOR ABNORMALITIES ASSOCIATED WITH LATE-LIFE PSYCHOSIS
Autore:
CALIGIURI MP; LOHR JB; PANTON D; HARRIS MJ;
Indirizzi:
UNIV CALIF SAN DIEGO,VA MED CTR,MOTOR FUNCT LAB V116,3350 LA JOLLA VILLAGE DR SAN DIEGO CA 92161 VET AFFAIRS MED CTR,GERIATR PSYCHIAT SERV SAN DIEGO CA 00000 SOUTHWOOD PSYCHIAT HOSP SAN DIEGO CA 00000 UNIV CALIF SAN DIEGO,SCH MED,DEPT PSYCHIAT LA JOLLA CA 92093
Titolo Testata:
Schizophrenia bulletin
fascicolo: 4, volume: 19, anno: 1993,
pagine: 747 - 754
SICI:
0586-7614(1993)19:4<747:EMAAWL>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALZHEIMERS-DISEASE; NEGATIVE SCHIZOPHRENIA; DOPAMINE; BRAIN; PARKINSONISM; TOMOGRAPHY; RECEPTORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social Sciences Citation Index
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
M.P. Caligiuri et al., "EXTRAPYRAMIDAL MOTOR ABNORMALITIES ASSOCIATED WITH LATE-LIFE PSYCHOSIS", Schizophrenia bulletin, 19(4), 1993, pp. 747-754

Abstract

Studies of extrapyramidal motor function in patients with schizophrenia have contributed to our understanding of the phenomenology and therapeutic outcome associated with neuroleptics. An increasing body of literature suggests that extrapyramidal motor abnormalities associated with schizophrenia may be linked to the pathophysiological mechanisms responsible for schizophrenia. Similarly, it has been documented that the extrapyramidal system may be involved in motor abnormalities in patients with Alzheimer's disease (AD). The present study was undertaken to examine motor function in schizophrenia and AD patients with psychosis. Quantitative instrumental procedures were used to examine rigidity, tremor, and bradykinesia in 13 neuroleptic-naive patients with schizophrenia, 13 AD patients with psychosis, and 26 age-comparable controls. Both schizophrenia and AD patients had significantly higher tremorand rigidity scores than did normal subjects. This comparative study of schizophrenia and AD patients with psychosis suggests that the effect of dementia in patients with psychosis is to prolong movement time,whereas abnormal parkinsonian postural tremor tends to be associated with psychosis in the absence of dementia.

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Documento generato il 05/04/20 alle ore 03:51:38