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Titolo:
DISPOSITION OF ENANTIOMERS OF SULTOPRIDE IN A HUMAN, RATS AND RABBITS
Autore:
KAMIZONO A; INOTSUME N; FUKUSHIMA S; NAKANO M;
Indirizzi:
KUMAMOTO UNIV HOSP,DEPT PHARMACEUT SERV,1-1-1 HONJO KUMAMOTO 860 JAPAN KUMAMOTO UNIV HOSP,DEPT PHARMACEUT SERV,1-1-1 HONJO KUMAMOTO 860 JAPAN
Titolo Testata:
Biological & pharmaceutical bulletin
fascicolo: 11, volume: 16, anno: 1993,
pagine: 1121 - 1123
SICI:
0918-6158(1993)16:11<1121:DOEOSI>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; SUBSTITUTED BENZAMIDE DRUGS; SULPIRIDE; BRAIN;
Keywords:
SULTOPRIDE; ENANTIOMER; STEREOSELECTIVE DISPOSITION; HUMAN; RAT; RABBIT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
A. Kamizono et al., "DISPOSITION OF ENANTIOMERS OF SULTOPRIDE IN A HUMAN, RATS AND RABBITS", Biological & pharmaceutical bulletin, 16(11), 1993, pp. 1121-1123

Abstract

Pharmacokineties of sultopride enantiomers was examined following a single dose in a human, rabbits and rats. Pharmacokinetic profiles weresimilar between (+)- and (-)-enantiomers of sultopride in human, whereas the serum concentrations of (-)-sultopride were slightly higher than those of (+)-sultopride after i.v. administration of 50 mg/kg of racemic sultopride to rats and rabbits.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 13:57:23