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Titolo:
GLUCOSE ENHANCEMENT OF MEMORY IN PATIENTS WITH PROBABLE SENILE DEMENTIA OF THE ALZHEIMERS TYPE
Autore:
MANNING CA; RAGOZZINO ME; GOLD PE;
Indirizzi:
UNIV VIRGINIA,HLTH SCI CTR,DEPT NEUROL,BOX 394 CHARLOTTESVILLE VA 22908 UNIV VIRGINIA,DEPT PSYCHOL,LIFE SCI LABS CHARLOTTESVILLE VA 22903
Titolo Testata:
Neurobiology of aging
fascicolo: 6, volume: 14, anno: 1993,
pagine: 523 - 528
SICI:
0197-4580(1993)14:6<523:GEOMIP>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPONTANEOUS-ALTERNATION PERFORMANCE; ACETYLCHOLINE SYNTHESIS; DOUBLE-BLIND; AGED HUMANS; DISEASE; BRAIN; DEFICITS; MICE; TETRAHYDROAMINOACRIDINE; MULTICENTER;
Keywords:
ALZHEIMERS DISEASE; MEMORY; GLUCOSE; AGING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
55
Recensione:
Indirizzi per estratti:
Citazione:
C.A. Manning et al., "GLUCOSE ENHANCEMENT OF MEMORY IN PATIENTS WITH PROBABLE SENILE DEMENTIA OF THE ALZHEIMERS TYPE", Neurobiology of aging, 14(6), 1993, pp. 523-528

Abstract

Attempts to attenuate the severe memory deficits in patients with SDAT have been largely unsuccessful, particularly in patients at advancedstages of the disease. Recent evidence indicates that glucose administration enhances memory in generally healthy aged rodents and humans. The present experiment demonstrates that glucose administration improves memory in moderately to severely demented patients with probable SDAT. Glucose ingestion significantly enhanced performance on several tests including orientation, word recognition and recall, narrative prose, and face recognition after glucose ingestion. Thus, the results extend enhancement of memory with glucose from generally healthy rodent and human populations to patients with probable SDAT.

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Documento generato il 07/07/20 alle ore 11:26:32