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Titolo:
HEPATITIS-C AND HEPATITIS-B SEROPREVALENC E IN PATIENTS INFECTED WITHTHE HUMAN-IMMUNODEFICIENCY-VIRUS IN PSYCHIATRIC-HOSPITALS
Autore:
GABASTOU JM; CHOUAKI T; ZEMIR A; MANGEOT J; MANUEL C; CORNEL E; DENISJACQUOT N; DEMAISON J; MAHUZIER G; BOURLIOUX P;
Indirizzi:
HOP PERRAY VAUCLUSE,CENT LAB F-91360 EPINAY SUR ORGE FRANCE
Titolo Testata:
Medecine et maladies infectieuses
fascicolo: 12, volume: 26, anno: 1996,
pagine: 1169 - 1172
SICI:
0399-077X(1996)26:12<1169:HAHSEI>2.0.ZU;2-6
Fonte:
ISI
Lingua:
FRE
Soggetto:
INTRAVENOUS-DRUG-USERS; HOMOSEXUAL MEN; PREVALENCE; HIV; HCV; ANTIBODY;
Keywords:
HIV; HCV; HBV; SYPHILIS; PREVALENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
J.M. Gabastou et al., "HEPATITIS-C AND HEPATITIS-B SEROPREVALENC E IN PATIENTS INFECTED WITHTHE HUMAN-IMMUNODEFICIENCY-VIRUS IN PSYCHIATRIC-HOSPITALS", Medecine et maladies infectieuses, 26(12), 1996, pp. 1169-1172

Abstract

The aim of this retrospective study, carried out between January 1992and April 1995 was to determine the prevalence and characteristics ofinfection by the hepatitis C virus for a population of HIV+ patients from five psychiatric hospitals in the Ile de France region. To this end, 117 HIV infected patients benefited from : a) a screening program for HCV, HBV, and syphilis antibodies and b) a dosage of transaminases. The associated risk factors were as follows: 64 % of HIV infected patients were drug addicts, 12 % were heterosexuals, 10 % were homosexuals, and 3 % had received a blood transfusion. The precise means of contamination was not established in 11 % of the cases. The prevalence ofHIV was 71 % but varied according to the means of contamination. No correlation was found between HCV seropositivity and an increased levelof transaminases, 80 % of patients were carriers of at least one hepatitis B marker antibody. The detection of the sole HBc antibody, in the absence of other HBV markers, appeared to be a good indirect marker of hepatitis C. Only 3 % of the patients were screened as responding well to vaccination against hepatitis B (isolated Ac HBs). 6 % of the patients were contaminated by all three viruses, HIV, HCV, and HBV. This study is the first to show, within the psychiatric sphere, that the prevalence of hepatitis C is considerably higher for HIV infected patients. Contamination through intravenous injection of drugs is the mostlikely cause of infection. A prospective follow up of HIV infected patients is therefore indispensable. Finally, the insufficient number ofpatients vaccinated against the hepatitis B virus should incite us torelaunch a vaccination programme in our hospital centers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/07/20 alle ore 06:02:40