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Titolo:
DETERMINATION OF IRON BY THE FERROCHEM-II - INTERFERENCE BY TUBERCULOSTATICS
Autore:
SANJOSE ME; SARANDESES A; ALVAREZ D; VALDES L; CHOMON B; DELRIO MJ;
Indirizzi:
HOSP PROV SANTIAGO,SERV ANAL CLIN,RUA RAMON BALTAR E-15706 SANTIAGO SPAIN HOSP PROV SANTIAGO,SERV NEUMOL E-15706 SANTIAGO SPAIN
Titolo Testata:
Scandinavian journal of clinical & laboratory investigation
fascicolo: 7, volume: 53, anno: 1993,
pagine: 653 - 658
SICI:
0036-5513(1993)53:7<653:DOIBTF>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Keywords:
ANALYTICAL INTERFERENCE; ETHAMBUTOL; IRON; ISONIAZID; PYRAZINAMIDE; RIFAMPICIN; TUBERCULOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
M.E. Sanjose et al., "DETERMINATION OF IRON BY THE FERROCHEM-II - INTERFERENCE BY TUBERCULOSTATICS", Scandinavian journal of clinical & laboratory investigation, 53(7), 1993, pp. 653-658

Abstract

Iron levels in samples from certain treated tuberculous patients are underestimated by the Ferrochem II analyser. Of the tuberculostatic drugs examined for a possible interference, isoniazid, ethambutol, rifampicin, pyrazinamide and Rifater(R) (a mixture of rifampicin, isoniazidand pyrazinamide), only pyrazinamide and Rifater(R) (due to its pyrazinamide content) were associated with iron levels differing significantly (p < 0.001) from those of controls, with means of -317.2 and -185.6 mumol l-1 for pyrazinamide and Rifater(R) respectively as against 9.91 mumol l-1 for the controls. The negative interference (I) due to pyrazinamide was independent of iron level in the samples but dependent on pyrazinamide concentration in the same (P) (r = 0.9993), I = -0.4380P - 0.4276.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 20:11:38