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Titolo:
SPONTANEOUS BACTERIAL PERITONITIS IN PATIENTS WITH CIRRHOSIS UNDERGOING SELECTIVE INTESTINAL DECONTAMINATION - A RETROSPECTIVE STUDY OF 229SPONTANEOUS BACTERIAL PERITONITIS EPISODES
Autore:
LLOVET JM; RODRIGUEZIGLESIAS P; MOITINHO E; PLANAS R; BATALLER R; NAVASA M; MENACHO M; PARDO A; CASTELLS A; CABRE E; ARROYO V; GASSULL MA; RODES J;
Indirizzi:
HOSP UNIV GERMANS TRIAS & PUJOL,DEPT GASTROENTEROL,CARRETERA CANYET S-N BADALONA 08916 SPAIN HOSP GERMANS TRIAS & PUJOL,DEPT GASTROENTEROL BADEN SWITZERLAND HOSP CLIN BARCELONA,LIVER UNIT BARCELONA CATALUNYA SPAIN
Titolo Testata:
Journal of hepatology
fascicolo: 1, volume: 26, anno: 1997,
pagine: 88 - 95
SICI:
0168-8278(1997)26:1<88:SBPIPW>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
MESENTERIC LYMPH-NODES; NEGATIVE NEUTROCYTIC ASCITES; PREDICTIVE FACTORS; GASTROINTESTINAL HEMORRHAGE; INDIGENOUS BACTERIA; CONTROLLED TRIAL; TRANSLOCATION; NORFLOXACIN; CIRRHOTICS; INFECTION;
Keywords:
CIRRHOSIS; GRAM-POSITIVE BACTERIA; SELECTIVE INTESTINAL DECONTAMINATION; SPONTANEOUS BACTERIAL PERITONITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
J.M. Llovet et al., "SPONTANEOUS BACTERIAL PERITONITIS IN PATIENTS WITH CIRRHOSIS UNDERGOING SELECTIVE INTESTINAL DECONTAMINATION - A RETROSPECTIVE STUDY OF 229SPONTANEOUS BACTERIAL PERITONITIS EPISODES", Journal of hepatology, 26(1), 1997, pp. 88-95

Abstract

Background/Aims: Selective intestinal decontamination with norfloxacin is widely used to prevent spontaneous bacterial infections in cirrhosis. The study was performed to compare the spontaneous bacterial peritonitis occurring in patients with and without prophylactic norfloxacin. Methods: Two hundred and twenty-nine consecutive episodes of spontaneous bacterial peritonitis, (193 in patients without (Group A) and 36in patients with norfloxacin prophylaxis (Group B)), were retrospectively analyzed. In 100 episodes (86 and 14, respectively), the responsible organism was isolated in ascitic fluid. Results: Clinical and laboratory data at diagnosis were comparable in both groups. There were marked differences (p<0.001) between group A and B in the frequency of peritonitis caused by gram-negative (67.4% vs. 14.3%) and gram-positive(30.2% vs. 78.6%) bacteria. There were three polymicrobial episodes, Bacteria resistant to cefotaxime and gram-negative bacilli resistant to quinolones were isolated in ascitic fluid in nine (seven in Group A and two in Group B) and three episodes (all in Group A), respectively. No differences in the course of infection and patient survival were observed between groups. Conclusions: Spontaneous bacterial peritonitisin patients with and without prophylaxis with norfloxacin are not different in clinical features, response to treatment and prognosis. Spontaneous bacterial peritonitis caused by gram-negative organisms resistant to quinolones is extremely uncommon in patients with cirrhosis receiving prophylactic norfloxacin.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 10:32:14