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Titolo:
MRI IN HYPERTROPHIC CARDIOMYOPATHY - A MORPHOFUNCTIONAL STUDY
Autore:
SARDANELLI F; MOLINARI G; PETILLO A; OTTONELLO C; PARODI RC; MASPERONE MA; SAITTA S; BASSO M; CAPONNETTO S;
Indirizzi:
INST RADIOL,VIALE BENEDETTO XV 10 I-16132 GENOA ITALY USL 12,DEPT CARDIOL GENOA ITALY UNIV GENOA,DEPT RADIOL I-16126 GENOA ITALY UNIV GENOA,DEPT CARDIOL I-16126 GENOA ITALY
Titolo Testata:
Journal of computer assisted tomography
fascicolo: 6, volume: 17, anno: 1993,
pagine: 862 - 872
SICI:
0363-8715(1993)17:6<862:MIHC-A>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR HYPERTROPHY; CINE MAGNETIC-RESONANCE; CLINICAL MANIFESTATIONS; VALVULAR REGURGITATION; PATHO-PHYSIOLOGY; IMAGES; INTERRELATIONS; GRADIENT; THERAPY; HEART;
Keywords:
HEART, FLOW DYNAMICS; HEART, DISEASES; MAGNETIC RESONANCE IMAGING, CINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
F. Sardanelli et al., "MRI IN HYPERTROPHIC CARDIOMYOPATHY - A MORPHOFUNCTIONAL STUDY", Journal of computer assisted tomography, 17(6), 1993, pp. 862-872

Abstract

Objective: We compared MRI with two-dimensional echocardiography (2dE) and Doppler echocardiography to determine the diagnostic role of MRIin hypertrophic cardiomyopathy (HCM). Materials and Methods: Twenty-three patients with 2dE diagnosis of HCM were examined with MRI; 12 of 23 patients were also studied by color (cDE) and continuous wave (cwDE) Doppler echocardiography. Morphologic information and diastolic heart wall thickness were obtained by SE sequences; functional study was performed by gradient echo sequences (cine MR). Results: The correlation between MR, SE sequences and 2dE was better for septal (r = 0.930, p< 0.01) than for posterolateral (r = 0.739, p < 0.01) wall thickness. The assessment of the distribution of the hypertrophy was changed by MR in five cases. Cine MR functional study showed a systolic subaorticsignal void (dynamic obstruction) in 12 of 22 patients and a systolicleft atrial signal void (mitral regurgitation) in 17 of 22. Systolic wall thickening was studied by cine MR and 2dE in 11 patients: A good correlation was found for septum (0.01 < p < 0.05) and a poor one for posterolateral wall (p > 0.05). The cine MR and cDE turbulence duration in the left ventricle and atrium showed excellent correlation (p < 0.01). Good agreement was found between the duration of subaortic turbulence (cine MR or cDE) and the pressure gradient (cwDE) (p < 0.01 and 0.01 < p < 0.05, respectively) and between cine MR and cDE semiquantitative estimate of the mitral regurgitation (p < 0.01). In all patientswith subaortic MR signal void studied with cwDE, a pressure gradient was present. Conclusion: Magnetic resonance imaging can play an important role in the diagnosis of HCM after 2dE-DE.

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Documento generato il 01/10/20 alle ore 03:06:48