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Titolo:
ROLE OF NITRIC-OXIDE IN MODULATING THE CHRONIC RENAL AND ARTERIAL-PRESSURE RESPONSES TO ANGIOTENSIN-II
Autore:
SCHNACKENBERG C; TUCKER B; PIGG K; GRANGER L;
Indirizzi:
UNIV MISSISSIPPI,MED CTR,DEPT PHYSIOL & BIOPHYS,2500 N STATE ST JACKSON MS 39216 UNIV MISSISSIPPI,MED CTR,DEPT PHYSIOL & BIOPHYS JACKSON MS 39216
Titolo Testata:
American journal of hypertension
fascicolo: 2, volume: 10, anno: 1997,
pagine: 226 - 229
SICI:
0895-7061(1997)10:2<226:RONIMT>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLOMERULAR-FILTRATION; DOG;
Keywords:
KIDNEY; HYPERTENSION; RENAL BLOOD FLOW DOG;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
C. Schnackenberg et al., "ROLE OF NITRIC-OXIDE IN MODULATING THE CHRONIC RENAL AND ARTERIAL-PRESSURE RESPONSES TO ANGIOTENSIN-II", American journal of hypertension, 10(2), 1997, pp. 226-229

Abstract

The purpose of this study was to determine longterm role of nitric oxide in modulating the chronic renal and arterial pressure responses toangiotensin II (AII). In normal dogs, intrarenal AII infusion (1.0 ng/kg/min) decreased renal plasma now (RPF) by 31% and glomerular filtration rate (GFR) by 17% and increased mean arterial pressure (MAP) by 22%. In dogs with chronic intrarenal NO synthesis blockade with N-omega-nitro-L-arginine methyl ester (3 mu g/kg/min), AII decreased RPF by 25% and GFR by 19%, and increased MAP by 7%. These data indicate that chronic inhibition of NO synthesis within the kidney attenuated the long-term renal and arterial pressure responses to All in dogs. (C) 1997 American Journal of Hypertension, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 02:47:45