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Titolo:
CARDIAC PHANTOM EVALUATION OF SIMULTANEOUSLY ACQUIRED DUAL-ISOTOPE REST TL-201 STRESS TC-99M SPECT IMAGES
Autore:
LOWE VJ; GREER KL; HANSON MW; JASZCZAK RJ; COLEMAN RE;
Indirizzi:
DUKE UNIV,MED CTR,DEPT RADIOL,NUCL MED SECT,BOX 3949 DURHAM NC 27710
Titolo Testata:
The Journal of nuclear medicine
fascicolo: 11, volume: 34, anno: 1993,
pagine: 1998 - 2006
SICI:
0161-5505(1993)34:11<1998:CPEOSA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; HEXAKIS 2-METHOXYISOBUTYL ISONITRILE; EMISSION COMPUTED-TOMOGRAPHY; METHOXY ISOBUTYL ISONITRILE; TC-99M SESTAMIBI; TL-201; PERFUSION; EXERCISE; REDISTRIBUTION; ARTERIOGRAPHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
V.J. Lowe et al., "CARDIAC PHANTOM EVALUATION OF SIMULTANEOUSLY ACQUIRED DUAL-ISOTOPE REST TL-201 STRESS TC-99M SPECT IMAGES", The Journal of nuclear medicine, 34(11), 1993, pp. 1998-2006

Abstract

Simultaneously acquired dual-isotope Tl-201/Tc-99m SPECT studies wereperformed using cardiac and thoracic phantoms to evaluate the dual-isotope myocardial perfusion technique. Cardiac phantom images representing infarction, viable myocardium and various levels of ischemia were analyzed. Studies with and without attenuating media were performed, and myocardium-to-defect count ratios and defect sizes from dual-isotope SPECT images were compared to myocardium-to-defect count ratios and defect sizes from single-isotope (Tl-201 and Tc-99m) SPECT images. Dual-isotope studies also were interpreted qualitatively. Studies with background activity simulating clinical conditions were performed and interpreted qualitatively. Myocardium-to-defect count ratios from both Tc-99m and Tl-201 were similar in single-isotope and dual-isotope SPECTimages. Thallium-201 and Tc-99m defect sizes were decreased slightly (mean +/- s.d., 1.0 +/- 1.7 cc for Tl-201 and 0.7 +/- 1.0 cc for Tc-99m) on dual studies when compared to single studies but were not statistically significant. Dual-isotope image simulations of normal, ischemic and infarcted and viable myocardium were correctly identified by experienced clinicians in 95% of the cases (21/22). Simultaneous dual-isotope Tl-201/Tc-99m SPECT imaging of cardiac phantoms produced images that had similar myocardium-to-defect count ratios to those produced using single-isotope techniques and were correctly evaluated on qualitative analysis. Changes in defect size related to dual-isotope imaging were minimal and not qualitatively important.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 10:11:39