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Titolo:
POPULATION-BASED STUDY OF SERUM HEPATITIS-B VIRUS-DNA IN GABON
Autore:
DAZZA MC; TREBUCQ A; GAUDEBOUT C; JARRETOU A; LEHESRAN JY; JOSSE R; DELAPORTE E; BRECHOT C; LAROUZE B;
Indirizzi:
HOP CLAUDE BERNARD,INSERM,U13,190 BLVD MACDONALD F-75019 PARIS FRANCE HOP CLAUDE BERNARD,INSERM,U13,190 BLVD MACDONALD F-75019 PARIS FRANCE OCEAC YAOUNDE CAMEROON CIRM FRANCEVILLE GABON INSERM,U370 F-75005 PARIS FRANCE
Titolo Testata:
Transactions of the Royal Society of Tropical Medicine and Hygiene
fascicolo: 5, volume: 87, anno: 1993,
pagine: 539 - 540
SICI:
0035-9203(1993)87:5<539:PSOSHV>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERINATAL TRANSMISSION; HBV-DNA; PREVENTION; INFECTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
M.C. Dazza et al., "POPULATION-BASED STUDY OF SERUM HEPATITIS-B VIRUS-DNA IN GABON", Transactions of the Royal Society of Tropical Medicine and Hygiene, 87(5), 1993, pp. 539-540

Abstract

The prevalence of serum hepatitis B virus (HBV) deoxyribonucleic acid(DNA) was measured in a Gabonese community at high risk for HBV infection. Among 698 subjects 5 to 24 years old, the prevalence of HBsAg was 11.1% vs. 57.9% for anti-HBs and 7.2% for anti-HBc alone. The prevalence of HBeAg among HBsAg-positive subjects was 26.5% vs. 59.5% for anti-HBe. The prevalence of HBV DNA tested by a hybridization spot test was 2. 1% in the overall population and 18.7% among HBsAg-positive subjects. HBV DNA was found in 15 of 21 HBeAg-positive subjects but in none of the subjects positive for anti-HBe or negative for both HBeAg and anti-HBe. HBV DNA was not detected in any HBsAg negative subjects. The prevalence of HBV DNA decreased with age. This low prevalence of HBV DNA contrasts with the high level of endemicity in the study population.

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Documento generato il 30/11/20 alle ore 10:02:47