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Titolo:
TRANSCATHETER CHEMOEMBOLIZATION OF PROGRESSIVE CARCINOID LIVER METASTASIS
Autore:
THERASSE E; BREITTMAYER F; ROCHE A; DEBAERE T; INDUSHEKAR S; DUCREUX M; LASSER P; ELIAS D; ROUGIER P;
Indirizzi:
HOSP HOTEL DIEU MONTREAL,DEPT DIAGNOST RADIOL,3840 ST URBAIN MONTREALH2W 1T7 PQ CANADA INST GUSTAVE ROUSSY,DEPT INTERVENT RADIOL F-94805 VILLEJUIF FRANCE
Titolo Testata:
Radiology
fascicolo: 2, volume: 189, anno: 1993,
pagine: 541 - 547
SICI:
0033-8419(1993)189:2<541:TCOPCL>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEPATIC-ARTERY EMBOLIZATION; HEPATOCELLULAR-CARCINOMA; IODIZED OIL; INTRAARTERIAL CHEMOTHERAPY; SURGICAL-TREATMENT; TUMORS; DEARTERIALIZATION; DOXORUBICIN; MANAGEMENT; NEOPLASIA;
Keywords:
ARTERIES, THERAPEUTIC BLOCKADE; CARCINOID; CHEMOTHERAPEUTIC INFUSION; LIVER NEOPLASMS, CHEMOTHERAPEUTIC INFUSION; LIVER NEOPLASMS, SECONDARY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
56
Recensione:
Indirizzi per estratti:
Citazione:
E. Therasse et al., "TRANSCATHETER CHEMOEMBOLIZATION OF PROGRESSIVE CARCINOID LIVER METASTASIS", Radiology, 189(2), 1993, pp. 541-547

Abstract

PURPOSE: The authors report their experience treating progressive liver metabases from carcinoid tumor with doxorubicin, iodized oil, and gelatin sponge embolization. MATERIALS AND METHODS: Of 23 patients, 18 had carcinoid syndrome and 19 had elevated urinary 5-hydroxyindoleacetic acid (5-HIAA) levels. Relief of symptoms, changes in 5-HIAA levels,and changes in tumor size could be evaluated in 10, 11, and 17 patients, respectively. RESULTS: Symptomatic response was complete (average duration, 29 months) in 70% and partial in 30% of evaluated patients. Biologic response was complete (average duration, 21 months) in 73%, partial in 18%, and minor in 9% of evaluated patients. Morphologic response was complete in 11%, partial in 24%, and minor in 24% of evaluated patients. Survival after diagnosis of primary tumor, diagnosis of hepatic metastases, and first chemoembolization was 81, 47, and 24 months, respectively. Eight patients were alive at the end of the study. Nomortality was related to chemoembolization. CONCLUSION. Chemoembolization is safe and effective for palliation of carcinoid liver metastases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 01:23:37