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Titolo:
LOCALIZATION OF A BAND 3-RELATED PROTEIN IN THE MITOCHONDRIA-RICH CELLS OF AMPHIBIAN SKIN EPITHELIUM
Autore:
DEVUYST O; ROTT R; DENEF JF; CRABBE J; KATZ U;
Indirizzi:
UCI,SCH MED,DEPT HISTOL,10 AVE HIPPOCRATE B-1200 BRUSSELS BELGIUM UCI,SCH MED,DEPT HISTOL,10 AVE HIPPOCRATE B-1200 BRUSSELS BELGIUM UCI,SCH MED,DEPT PHYSIOL B-1200 BRUSSELS BELGIUM TECHNION ISRAEL INST TECHNOL,DEPT BIOL IL-32000 HAIFA ISRAEL
Titolo Testata:
Biology of the cell
fascicolo: 3, volume: 78, anno: 1993,
pagine: 217 - 221
SICI:
0248-4900(1993)78:3<217:LOAB3P>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-ERYTHROCYTE; COLLECTING DUCT; TOAD SKIN; CHLORIDE TRANSPORT; ANION-EXCHANGER; MEMBRANE; ATPASE; CONDUCTANCE; POLYPEPTIDE; BLADDER;
Keywords:
AMPHIBIAN SKIN; ANION EXCHANGE; BAND-3; CHLORIDE PERMEABILITY; MITOCHONDRIA-RICH CELLS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
O. Devuyst et al., "LOCALIZATION OF A BAND 3-RELATED PROTEIN IN THE MITOCHONDRIA-RICH CELLS OF AMPHIBIAN SKIN EPITHELIUM", Biology of the cell, 78(3), 1993, pp. 217-221

Abstract

Based on immunoblotting procedure, the isolated epithelium of amphibian skin was found to contain a 180 kDa protein which cross-reacts witha polyclonal antiserum raised against human erythrocyte Band 3. Immunoperoxidase and immunofluorescence staining techniques indicated that the Band 3-related protein was localized in the mitochondria-rich cells (MRC) of this epithelium, with characteristic apical labelling pattern. Our findings show that the putative apical anion exchanger of the MRC is immunologically related to the band 3 multigenic family, which catalyzes Cl--HCO3- transmembranous exchange. It thus suggests a molecular basis for the role played by these cells in the transepithelial Cl- pathway and acid-base regulation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 18:38:40