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Titolo:
PRELIMINARY EXPERIENCE WITH THE APPLICATION OF GADOLINIUM-DTPA BEFOREMR IMAGING-GUIDED LASER-INDUCED INTERSTITIAL THERMOTHERAPY OF BRAIN-TUMORS
Autore:
KAHN T; HARTH T; BETTAG M; SCHWABE B; ULRICH F; SCHWARZMAIER HJ; MODDER U;
Indirizzi:
UNIV DUSSELDORF,INST DIAGNOST RADIOL,MOORENSTR 5 D-40225 DUSSELDORF GERMANY
Titolo Testata:
Journal of magnetic resonance imaging
fascicolo: 1, volume: 7, anno: 1997,
pagine: 226 - 229
SICI:
1053-1807(1997)7:1<226:PEWTAO>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
TISSUE; PHOTOCOAGULATION; PHOTOTHERAPY; ABLATION; MODEL;
Keywords:
BRAIN NEOPLASMS, MR; MR, GUIDANCE; LASERS; LASERS, INTERSTITIAL THERAPY; GADOLINIUM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
T. Kahn et al., "PRELIMINARY EXPERIENCE WITH THE APPLICATION OF GADOLINIUM-DTPA BEFOREMR IMAGING-GUIDED LASER-INDUCED INTERSTITIAL THERMOTHERAPY OF BRAIN-TUMORS", Journal of magnetic resonance imaging, 7(1), 1997, pp. 226-229

Abstract

The purpose of this study was to investigate the potential value of i.v. gadolinium-diethylenetriamine penta-acetic acid (Gd-DTPA) applied before MRI-guided laser-induced interstitial thermotherapy (LITT) of brain tumors without original enhancement, especially in defining totallesion size during therapy. MRI-guided LITT was performed on two patients with astrocytoma WHO II. For both patients, Gd-DTPA was administered intravenously after a first irradiation period and LITT was continued after pulling back the light guide to coagulate the upper parts ofthe tumor. In both patients, the whole irreversible damaged zone of the second irradiation period after Gd-DTPA showed an intense increase of signal intensity. The spatial expansion correlated with the diameter of an enhancing rim after Gd-DTPA on follow-np studies. Our preliminary results indicate that the application of Gd-DTPA before MRI-guidedLITT may be of value in defining exactly the size of the irreversibledamaged zone during therapy in nonenhancing brain tumors.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 01:55:04