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Titolo:
PLASMA BETA-ENDORPHIN LEVELS, NALTREXONE, AND HALOPERIDOL IN AUTISTIC-CHILDREN
Autore:
ERNST M; DEVI L; SILVA RR; GONZALEZ NM; SMALL AM; MALONE RP; CAMPBELL M;
Indirizzi:
NYU MED CTR,DEPT PSYCHIAT,550 1ST AVE NEW YORK NY 10016 NYU MED CTR,DEPT PSYCHIAT,550 1ST AVE NEW YORK NY 10016 NYU MED CTR,DEPT PHARMACOL NEW YORK NY 10016
Titolo Testata:
Psychopharmacology bulletin
fascicolo: 2, volume: 29, anno: 1993,
pagine: 221 - 227
SICI:
0048-5764(1993)29:2<221:PBLNAH>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
INFANTILE-AUTISM; DOUBLE-BLIND; RAT; EFFICACY; CORTISOL; OPIATE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
M. Ernst et al., "PLASMA BETA-ENDORPHIN LEVELS, NALTREXONE, AND HALOPERIDOL IN AUTISTIC-CHILDREN", Psychopharmacology bulletin, 29(2), 1993, pp. 221-227

Abstract

Plasma beta-endorphin levels were measured in 13 autistic children, aged 3.67 to 11.67 years at the end of treatment (naltrexone, haloperidol, pimozide, or placebo) and in 5 of the 13 children also at baseline. Baseline plasma beta-endorphin levels were lower than those reportedin the literature. There was a strong correlation between plasma beta-endorphin levels and severity of sterotypies in all children. Naltrexone did not seem to have a specific effect on plasma beta-endorphin levels; short-term haloperidol treatment was associated with an increase, whereas long-term haloperidol treatment seemed to have a depressive effect on plasma beta-endorphin levels, which rose after withdrawal ofhaloperidol.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 17:03:31