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Titolo:
POOR SURVIVAL OF BLACK PATIENTS IN CARCINOMA OF THE ENDOMETRIUM
Autore:
AZIZ H; ROTMAN M; HUSSAIN F; SMITH G; CHAN E; CHOI K; SOHN C; HALPERN J; SCHWARTZ D; ARAL I; FRUCHTER R; SERUR E;
Indirizzi:
SUNY DOWNSTATE MED CTR,DEPT RADIAT ONCOL,450 CLARKSON AVE,BOX 1211 BROOKLYN NY 11203 SUNY DOWNSTATE MED CTR,HLTH SCI CTR,DEPT GYNECOL & OBSTET BROOKLYN NY11203 SUNY DOWNSTATE MED CTR,HLTH SCI CTR,CTR SCI COMP BROOKLYN NY 11203
Titolo Testata:
International journal of radiation oncology, biology, physics
fascicolo: 2, volume: 27, anno: 1993,
pagine: 293 - 301
SICI:
0360-3016(1993)27:2<293:PSOBPI>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROGNOSTIC FACTORS; SOCIOECONOMIC-FACTORS; WHITE DIFFERENCES; CANCER INCIDENCE; PROSTATE-CANCER; UNITED-STATES; ADENOCARCINOMA; ESTROGENS; THERAPY; IRRADIATION;
Keywords:
CARCINOMA OF ENDOMETRIUM; RACIAL DIFFERENCES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
48
Recensione:
Indirizzi per estratti:
Citazione:
H. Aziz et al., "POOR SURVIVAL OF BLACK PATIENTS IN CARCINOMA OF THE ENDOMETRIUM", International journal of radiation oncology, biology, physics, 27(2), 1993, pp. 293-301

Abstract

Purpose: To compare the prognostic factors and survivals of black andwhite patients with endometrial carcinoma. Methods and Materials: A retrospective study was undertaken of a total of 290 patients with endometrial carcinoma who were treated similarly at the Health Science Center at Brooklyn and Kings County Hospital Center from 1975 and 1990. One hundred and thirty-six of 290 (47.2%) were black and 135/290 (46.9%) were white. Well-known prognostic factors affecting endometrial carcinoma were studied in black and white group of patients. Their overallsurvival and comparison of survival in each prognostic group were also estimated using multi-variate analysis. Results: Fifty-four percent of white patients had Stage I disease, compared to 45.9% in black patients. In Stage II, 51.6% were white and 48.4% were black, and in StageIII, 88.89% were black and 11.1% were white patients (p = 0.034). Fifty six percent Grade I patients were white and 44% were black. In grade 2, 53.3% were white and 46.7% were black and in Grade 3 disease, 70.5% were black and 29.5% were white (p = 0.008). Up to the inner third of myometrial invasion had occurred in 60.6% of white patients and 39.4% in black patients. The middle third of the myometrium was invaded in 60.7% of white patients, and 39.3% of black patients. Thirty-seven percent of outer third of myometrial invasion was found in white patients and 63% in black patients (p = 0.038). Seventy-two percent of positive lymph nodes were found in black patients and 28.0% in white patients (p = 0.01). Sixty-one percent of patients with positive peritoneal cytology were black as compared to 38.7% in white patients (p = 0.017). The overall ten-year corrected survival for white and black patientswas 72% and 40%, respectively (p = 0.0003). Survivals comparisons, when stratified by race and each prognostic group, showed statistically significant overall survival differences in favor of white patients. Conclusion: Black patients with endometrial carcinoma have poor survival. Low socio-economic status (SES) would not explain these findings. More research is required to determine the cause of poor survival in black patients with endometrial carcinoma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 17:36:19