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Titolo:
AUTONOMIC CONTROL OF ADRENAL-FUNCTION
Autore:
EDWARDS AV; JONES CT;
Indirizzi:
UNIV CAMBRIDGE,PHYSIOL LAB,DOWNING ST CAMBRIDGE CB3 2EG ENGLAND INST MOLEC MED,CELLULAR & DEV PHYSIOL LAB OXFORD ENGLAND
Titolo Testata:
Journal of Anatomy
, volume: 183, anno: 1993,
parte:, 2
pagine: 291 - 307
SICI:
0021-8782(1993)183:<291:ACOA>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPLANCHNIC NERVE-STIMULATION; VASOACTIVE-INTESTINAL-PEPTIDE; CORTICOTROPIN-RELEASING-FACTOR; CONSCIOUS HYPOPHYSECTOMIZED CALVES; ENKEPHALIN-LIKE IMMUNOREACTIVITY; FASCICULATA-RETICULARIS CELLS; BETA-ADRENERGIC STIMULATION; NICOTINE-INDUCED SECRETION; GENE-RELATED PEPTIDE; CHROMAFFIN CELLS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
155
Recensione:
Indirizzi per estratti:
Citazione:
A.V. Edwards e C.T. Jones, "AUTONOMIC CONTROL OF ADRENAL-FUNCTION", Journal of Anatomy, 183, 1993, pp. 291-307

Abstract

Recent studies of adrenal function in conscious calves are reviewed. These have involved collecting the whole of the adrenal effluent bloodfrom the right adrenal gland at intervals and, where necessary, priorfunctional hypophysectomy by destruction of the pituitary stalk undergeneral halothane anaesthesia 3 d previously. The adrenal medulla wasfound to release numerous neuropeptides, in addition to catecholamines, in response to stimulation of the peripheral end of the right splanchnic nerve, which was carried out below behavioural threshold. Many of these responses were enhanced by stimulating intermittently at a relatively high frequency. Intra-aortic infusions of a relatively low dose of acetylcholine (4.5 nmol min-1 kg-1) elicited similar responses. In the adrenal cortex, agonists which either potentiated the steroidogenic response to ACTH or exerted a direct steroidogenic action includedVIP, CGRP, CRF and ACh acting via muscarinic receptors. Stimulation of the peripheral end of the right splanchnic nerve strongly potentiated the steroidogenic response to ACTH and there is compelling evidence that the innervation normally plays an important part in cortisol secretion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 12:49:17