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Titolo:
VOLUMETRIC-ANALYSIS OF URINARY ERYTHROCYT ES IN THE ETIOLOGIC DIAGNOSIS OF HEMATURIA
Autore:
JEAN G; FRANCOIS B; DRAI J; PELLET H; DURIEU I; CAHEN R; TROLLIET P;
Indirizzi:
CHU LYON SUD,SERV NEPHROL HEMODIALYSE TRANSPLANTAT F-69310 PIERRE BENITE FRANCE CHU LYON SUD,SERV BIOCHIM F-69310 PIERRE BENITE FRANCE HOP EDOUARD HERRIOT,SERV CYTOL F-69437 LYON 3 FRANCE
Titolo Testata:
La Presse medicale
fascicolo: 30, volume: 22, anno: 1993,
pagine: 1392 -
SICI:
0755-4982(1993)22:30<1392:VOUEEI>2.0.ZU;2-A
Fonte:
ISI
Lingua:
FRE
Soggetto:
PHASE-CONTRAST MICROSCOPY; GLOMERULAR HEMATURIA; DISTRIBUTION CURVES; MORPHOLOGY;
Keywords:
HEMATURIA; VOLUMETRIC ANALYSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
G. Jean et al., "VOLUMETRIC-ANALYSIS OF URINARY ERYTHROCYT ES IN THE ETIOLOGIC DIAGNOSIS OF HEMATURIA", La Presse medicale, 22(30), 1993, pp. 1392

Abstract

Intravenous pyelography and cystography may fail to localize the origin of haematuria. Microhaematuria is known to be present in 2 to 10 percent of the general population, usually without pathological consequences. Study of red cell morphology by phase contrast microscopy is effective in distinguishing between <<glomerular>> (from renal tissue) and <<non-glomerular>> (from urinary tract) erythrocytes, but this technique is not currently available in all laboratories. Urinary blood cell volume analysis has been presented as a simple and automatic alternative method. We compared these two techniques in 100 cases of haematuria of various origins. The cut-off point between glomerular and non-glomerular erythrocytes was set at 71 fl. Phase contrast microscopy always confirmed the clinical and/or histological diagnosis, but volume analysis did not: mean erythrocyte volume of glomerular origin was 66.6 /- 10.4 fl, while non-glomerular volume was 94.5 +/- 17 fl (P < 0.001); cell volume analysis was confirmative in only 72 percent of all diagnoses (65 percent of microhaematurias, 83 percent of macrohaematurias); sensitivity was 65 percent and specificity 85 percent for glomerular erythrocytes. Due to poor performance, urinary red volume analysis is not an acceptable alternative method to phase contrast microscopy when searching for the site of bleeding.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 15:21:53