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Titolo:
MUTY REPAIR IS MUTAGENIC IN MUTT(-) STRAINS OF ESCHERICHIA-COLI
Autore:
VIDMAR JJ; CUPPLES CG;
Indirizzi:
CONCORDIA UNIV,DEPT BIOL,1455 MAISONNEUVE BLVD W MONTREAL H3G 1M8 QUEBEC CANADA CONCORDIA UNIV,DEPT BIOL,1455 MAISONNEUVE BLVD W MONTREAL H3G 1M8 QUEBEC CANADA
Titolo Testata:
Canadian journal of microbiology
fascicolo: 9, volume: 39, anno: 1993,
pagine: 892 - 894
SICI:
0008-4166(1993)39:9<892:MRIMIM>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
G-A MISPAIRS; DNA GLYCOSYLASE; G.C->T.A TRANSVERSIONS; MISMATCH CORRECTION; GENE-PRODUCT; MUTATOR GENE; PROTEIN; ABUNDANCE; MUTATIONS; SUBSTRATE;
Keywords:
MUTT; MUTY; ESCHERICHIA-COLI MUTATOR STRAINS;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
J.J. Vidmar e C.G. Cupples, "MUTY REPAIR IS MUTAGENIC IN MUTT(-) STRAINS OF ESCHERICHIA-COLI", Canadian journal of microbiology, 39(9), 1993, pp. 892-894

Abstract

We have determined the numbers and types of mutations that occur in strains of Escherichia coli defective in mutT and (or) mutY repair. High rates of C . G to A . T mutations in mutY- cells are unaffected by the status of mutT. However, mutT-/mutY+ strains have higher rates of A. T to C . G mutations than mutT-/mutY- strains. This result indicates that the high rates of A . T to C . G mutations seen in mutT- strains of E. coli are due in part to the activity of the mutY repair system. We conclude that mutY repair is mutagenic in a mutT- background.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 11:37:34