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Titolo:
DISTRIBUTION OF ESTROGEN RECEPTOR-IMMUNOREACTIVE CELLS IN THE SHEEP BRAIN
Autore:
LEHMAN MN; EBLING FJP; MOENTER SM; KARSCH FJ;
Indirizzi:
UNIV CALIF SAN FRANCISCO,DEPT OBSTET & GYNECOL,CTR REPROD ENDOCRINOL,BOX 0556 SAN FRANCISCO CA 94143 UNIV CINCINNATI,COLL MED,DEPT ANAT & CELL BIOL CINCINNATI OH 45267 UNIV MICHIGAN,REPROD SCI PROGRAM ANN ARBOR MI 48109
Titolo Testata:
Endocrinology
fascicolo: 2, volume: 133, anno: 1993,
pagine: 876 - 886
SICI:
0013-7227(1993)133:2<876:DOERCI>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
LUTEINIZING-HORMONE SECRETION; MEDIAL BASAL HYPOTHALAMUS; GUINEA-PIG BRAIN; FEMALE RAT; PREOPTIC AREA; IMMUNOCYTOCHEMICAL LOCALIZATION; SEASONAL REPRODUCTION; CONCENTRATING CELLS; NEURONS; ESTRADIOL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
63
Recensione:
Indirizzi per estratti:
Citazione:
M.N. Lehman et al., "DISTRIBUTION OF ESTROGEN RECEPTOR-IMMUNOREACTIVE CELLS IN THE SHEEP BRAIN", Endocrinology, 133(2), 1993, pp. 876-886

Abstract

The distribution of immunoreactive (IR) estrogen receptor (ER)-containing cells was studied in the brains of adult Suffolk ewes using a ratmonoclonal antibody (H222) which recognizes the human estrogen receptor. IR cells were characterized by dense nuclear reaction product, andin some instances, cytoplasmic immunostaining which filled dendrite-like processes. The greatest densities of ER-IR cells were found in themedial preoptic area, the mediobasal hypothalamus, and in a number oflimbic system structures (amygdala, bed nucleus of the stria terminalis, lateral septum). ER-IR cells were found at lower densities in several other subregions of the hypothalamus and limbic system, and in theperiaqueductal gray of the caudal midbrain. Cytoplasmic ER immunoreactivity was most prominent among ER-IR cells in the ventrolateral-ventromedial nucleus, the bed nucleus of the stria terminalis, the midbrainperiaqueductal gray, and some ER-IR cells in the substantia innominata. The distribution of ER-containing cells in the sheep brain closely parallels that seen in other mammals. ER-IR cells are found in sites such as the medial preoptic area and ventrolateral-ventromedial hypothalamus which have been implicated as targets in this species and othersfor the influence of estradiol on sexual behavior and reproductive neuroendocrine function.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 07:36:24